Predicting change, brains, trains and mental health

State Awards

“Trait-based ecology” enables Macquarie University’s Mark Westoby to explain patterns of species occurrence and abundance and to understand the impacts of climate change and changing patterns of land use. He received the $55,000 NSW Scientist of the Year.

Nanocapsules for drugs delivery: Frank Caruso is making miniature capsules that could better deliver drugs for cancer, AIDS and cardiovascular diseases. He won one of the 2014 Victoria Prizes for Science & Innovation worth $50,000.

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Australian Academy of Science Early-career Awards

Julie Arblaster’s climate research is helping to explain the climate of the Australian region, particularly the ozone hole, El Niño, the monsoon, and Australian rainfall variability.

David Warton is driving data analysis in ecology, making it a more predictive science. His tools are influencing statistics across science and industry.

Christian Turney has pioneered new ways of combining climate models with records of past climate change spanning from hundreds to thousands of years.

Maria Seton has redefined the way we reconstruct the movement of continental plates and contributed to studies on the effect ocean basin changes have had on global long-term sea level and ocean chemistry. Continue reading Australian Academy of Science Early-career Awards

Australian Academy of Science medals

Harry Messel has been a powerful force in science education—from the Physics Foundation to textbooks and his establishment of International Science Schools. He was awarded the Academy Medal.

Simon McKeon is a prominent business leader and philanthropist who has made extensive contributions to Australian science and innovation including chairing the CSIRO Board and the agenda-setting McKeon report into medical research in Australia. He was awarded the Academy Medal.

The life and death of cells: Jerry Adams has advanced understanding of cancer development, particularly of genes activated by chromosome translocation in lymphomas. By clarifying how the Bcl-2 protein family controls the life and death of cells, he and his colleagues at the Walter and Eliza Hall Institute of Medical Research have galvanised the development of a promising new class of anti-cancer drugs. Jerry was awarded the 2014 Macfarlane Burnet Medal. Continue reading Australian Academy of Science medals

Changing lives: Australia–Japan science links

Japanese science changing Australia

The impact of Japanese technological prowess on Australian society is obvious for all to see. How we listened to music was transformed by audio recording technologies: from the Walkman to the CD.

Nobel Laureate Shinya Yamanaka changed stem cell science. Credit: Gladstone Institutes/Chris Goodfellow
Nobel Laureate Shinya Yamanaka changed stem cell science. Credit: Gladstone Institutes/Chris Goodfellow

Home entertainment was changed by video tapes, DVDs, and game consoles. We rely on Japanese innovation in transport—reliable car engineering, the lean manufacturing techniques that made them affordable and, more recently, hybrid cars.

Fundamental science discoveries are now bringing a new era of transformation. Japanese researchers were honoured last year with the Nobel Prize for their invention of the blue LED. They succeeded where for 30 years everyone else had failed. Incandescent light bulbs lit the 20th century; the 21st century will be lit by LED lamps— lasting a lifetime and using a fraction of the energy.

In 2006 Shinya Yamanaka discovered how intact mature cells in mice could be reprogrammed to become immature stem cells. By introducing only a few genes, he could reprogram mature cells to become pluripotent stem cells, that is, immature cells that are able to develop into all types of cells in the body. His work is transforming stem cell medicine and many Australian researchers are now using his induced pluripotent stem cells to develop stem cell medicine.

Australian science changing Japan

It’s not a one way trade. Japanese lives are being improved by Australian inventions such as the bionic ear, gum that repairs tooth decay, sleep disorder treatments, lithium to treat bipolar disorder, aircraft black boxes, and anti-flu drugs, which are all in daily use in Japan.

And when you connect to a fast and reliable wi-fi network you can thank Australian astronomers who were searching for black holes and created tools for cleaning up radio waves.

Collaborating for the future

Today there are hundreds of thriving Australia–Japan research collaborations, many of which will have a profound impact on our lives in the years ahead.

Over the past five years, Japan has consistently placed within the 10 countries that have the highest number of collaborations with Australian researchers on Australian Research Council–funded projects. The ARC reports that the most popular disciplines for collaboration with Japan are: material engineering; biochemistry and cell biology; atomic, molecular, nuclear, particle and plasma physics; astronomical and space sciences and plant biology.

Other collaborations

Seeing every cell in a whole adult brain
Scientists from RIKEN, the University of Tokyo, JAST, and the Queensland University of Technology have developed CUBIC—a technique for rapidly imaging the brain. They believe it will be scalable to whole bodies.

Biomedical applications for ‘magic crystals’
CSIRO and Osaka Prefecture University are developing biomedical applications for the massively absorbent metal–organic framework crystals developed by CSIRO.

How our phones track us
Billions of us now have phones that tell us and others where we are and what’s around us. A team from RMIT, Intel, Fudan University and Keio University is exploring the cross-cultural and intergenerational study of this phenomenon, and the implications for privacy, in three key sites: Tokyo, Shanghai and Melbourne.

For more information: Science in Public, www.scienceinpublic.com.au/stories/japan

Chocolate and iron for speedy drug delivery

Natural phenols, such as those found in chocolate, and minerals such as iron are being used to develop fast, economical drug-delivery capsules.

Frank Caruso is creating nano-packages for drug delivery. Credit: Richard Timbury, Casamento Photography
Frank Caruso is creating nano-packages for drug delivery. Credit: Richard Timbury, Casamento Photography

Frank Caruso and his team at The University of Melbourne are making nano-sized capsules that will encase vaccines and protect them from being broken down when entering the body. They believe that this delivery system will be biologically friendly and overcome a major challenge for medical materials: their compatibility with living systems.

One of the challenges of treating diseases such as cancer and HIV is delivering treatment with minimal damage to healthy areas.

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