The brain’s specialist cleaning cells play a key role in neurodegenerative diseases, and they may also hold the secret to new treatments for the likes of MS and Alzheimer’s.
Professor Colin Pouton and his team at the Monash Institute of Pharmaceutical Sciences found a way to isolate microglia, the immune cells of the brain, from stem cells. Better yet, they made the cells fluorescent so their activity can be tracked, opening up new avenues of research.
Professor Trevor Kilpatrick and his colleagues at the Florey Institute of Neuroscience and Mental Health think Colin’s engineered cells just might be the key to creating a revolutionary treatment for multiple sclerosis. Continue reading Enlisting the brain’s immune cells to fight MS
The idea that long-term memory might be stored in our brain’s DNA is being tested by Professor Geoff Faulkner, using brains affected by Alzheimer’s.
Geoff has already shown that the DNA in our brains is different to the DNA in the rest of our bodies and that it changes as we learn. He’s proposing that these changes are associated with how we store our long-term memories.
More recently, he’s linked these differences to the function of genes in the hippocampus, the part of the brain that controls memory and spatial navigation, and has been implicated in memory loss with ageing, schizophrenia and Alzheimer’s disease. Continue reading Are memories stored in DNA?
“Trait-based ecology” enables Macquarie University’s Mark Westoby to explain patterns of species occurrence and abundance and to understand the impacts of climate change and changing patterns of land use. He received the $55,000 NSW Scientist of the Year.
Nanocapsules for drugs delivery: Frank Caruso is making miniature capsules that could better deliver drugs for cancer, AIDS and cardiovascular diseases. He won one of the 2014 Victoria Prizes for Science & Innovation worth $50,000.
Continue reading Predicting change, brains, trains and mental health
Not satisfied with transforming plant biology and stem cell science, The University of Western Australia’s Ryan Lister is also tacking the human brain.
Continue reading Unwrapping brain development
Kaylene Young believes she can persuade lazy stem cells in our brain to repair brain injuries and even treat diseases such as multiple sclerosis and Alzheimer’s.
Continue reading Repairing the brain with its own stem cells