All posts by Operations

Making polymers with light

Polymers are being used for non-stick coatings, anti-fouling technology, precision drug delivery, medical diagnosis, imaging, and many other applications.

Cyrille Boyer (Photo credit: Prime Minister’s Prizes for Science/WildBear)
Cyrille uses light to make new and complex polymers. Credit: Prime Minister’s Prizes for Science/WildBear

Associate Professor Cyrille Boyer’s ideas are built on the revolutionary RAFT techniques (a technique to precisely control how small molecules are linked together to form large polymer chains) for which Professor David Solomon and Dr Ezio Rizzardo received the 2011 Prime Minister’s Prize for Science. His latest technology uses light and chlorophyll to catalyse the production of polymers.

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Fighting stroke damage

A drug based on a molecule naturally present in infants – but which declines in adulthood – can halve the scarring in brains of those who have suffered stroke. And it can be delivered up to a week afterward.

The drug developed by James and Leon minimises the amount of scarring after the wound has been stabilised. Credit: Leon Teo
Enlarged cell bodies (pink), with increased scar-forming (green) following stroke. Credit: Leon Teo

“We hope our work will improve the recovery of the elderly, as well as people in rural and remote communities, who haven’t had access to speedy treatment following a stroke,” says Associate Professor James Bourne at the Australian Regenerative Medicine Institute (ARMI ), and Chief Investigator of the research.
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Improved primary science teaching at no extra cost

Two science teachers from New South Wales and Queensland are using fresh approaches to get kids interested in science – and keep them interested.

Ken Silburn (Photo credit: Prime Minister’s Prizes for Science/WildBear)
Casula High School has gone from just eight students taking science to two-thirds of Year 11 and 12 students. Credit: Prime Minister’s Prizes for Science/WildBear

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Head to tail: the molecules that tell you how to grow a backbone

Growing the right number of vertebrae in the right places is an important job – and scientists have found the molecules that act like ‘theatre directors’ for vertebrae genes in mice: telling them how much or how little to express themselves.

Edwina and her team were able to visualise the formation of the skeleton, using stains for bone (red) and cartilage (blue). Credit: Edwina McGlinn
Edwina and her team were able to visualise the formation of the skeleton, using stains for bone (red) and cartilage (blue). Credit: Edwina McGlinn

The finding may give insight into how the body-shapes of different species of animals evolved, since the molecules under scrutiny are present in a wide range of animals – ranging from fish to snakes to humans.

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Trillions of bubbles at work for Australia

Graeme Jameson’s technologies use trillions of bubbles to add billions of dollars to the value of Australia’s mineral and energy industries.

Graeme took flotation, a century-old technology developed in Broken Hill, and transformed it. A turbulent cloud of minute bubbles are pushed through a slurry of ground-up ore where they pick up tiny mineral particles and carry them to the surface.

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Making blood on demand

‘Buddy’ cells that trigger blood stem cells to fully-develop have been discovered by a team of Australian scientists. The finding, in zebrafish, may hold the key to creating blood on demand in the lab.

Everyday medical procedures can require litres of donated blood; and blood stem cells – which can turn into any one of the different types of blood cell – are often used in treatments for leukaemia, lymphoma, and other blood cancers.

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Unboiling an egg

Scientists in Australia and California have worked out how to unboil an egg. It may sound like an odd discovery, but it’s changed the way scientists think about manipulating proteins, an industry worth AU$160 billion per year.

Flinders University Professor Colin Raston and his team have developed Vortex Fluid Technology – using mechanical energy, or spinning, to reverse the effects of thermal energy, or boiling.

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Where are the plants and animals we want to conserve, and the invaders we want to control?

Jane Elith is one of the most influential environmental scientists in the world, though she rarely ventures into the field.

Jane Elith (Photo credit: Prime Minister’s Prizes for Science/WildBear)
In the field of environment and ecology, Jane is the 11th most cited author worldwide over the past 10 years. Credit: Prime Minister’s Prizes for Science/WildBear

She develops and assesses species distribution models, which are used by governments, land and catchment managers and conservationists around the world—in short, for applying the lessons of ecology.

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Press print for more body parts

“You can’t teach anatomy without bodies. Or at least you couldn’t until now,” says Monash University’s Paul McMenamin.

He and his colleagues are printing 3D plastic body parts of unprecedented detail and accuracy that have the potential to revolutionise anatomy teaching.

The printed parts will hold up to repeated handling and close study. Credit: Centre for Human Anatomy Education
The printed parts will hold up to repeated handling and close study. Credit: Centre for Human Anatomy Education

Anatomy students need a high degree of familiarity with the intricate details of the human body. That ideally comes with repeated handling and hands-on study. But students are often reluctant to touch a cadaver any more than necessary.

Removing the emotional, ethical and physical restrictions to close handling and repeated study improves the students’ familiarity with the human body. Another advantage of the printing is the expertly applied false colouring picking out intricate nerves, veins, arteries and ligaments that are much harder to identify in preserved cadavers.

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Blood reveals Great Barrier Reef sharks as homebodies

Small Australian sharks have been exposed as bigger homebodies than previously thought, in a study that took an existing chemical tracking technique and made it work for Great Barrier Reef sharks.

Dr Sam Munroe in the field
Dr Sam Munroe working in the field, Cleveland Bay, Queensland

The study found that the travel history of the Australian sharpnose shark was written in their blood—with chemical ‘fin-prints’ showing they tended to stay within smaller areas than previously believed.

“Small-bodied sharks that are both predator and prey, such as the Australian sharpnose, may be particularly important links between food webs,” says lead researcher Dr Sam Munroe, who studied the sharks while at James Cook University in Townsville.

“Information on their movements can improve our understanding of how the ecosystems function, while also helping us predict species most at risk from the impacts of a changing environment.”

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