The world’s meat production could be lifted by 10 to 15 per cent if a vaccine can be found to combat the liver fluke.
Juvenile liver fluke parasites which cause serious disease in livestock and humans. Credit: D Piedrafita (Monash); T Spithill (La Trobe).This is the aim of a collaborative bioscience group at the new $288 million Centre for AgriBioscience (AgriBio).
An effective vaccine against liver fluke could not only boost meat production but would also lead to a large reduction in the amount of drugs given to livestock, says Prof Terry Spithill, who is co-director of AgriBio and based at La Trobe University. Continue reading Stopping parasite means more, safer meat→
How do the power plants of the cell—the mitochondria—use their defence mechanisms to fight diseases such as Parkinson’s disease? This debilitating disorder is caused by an accumulation of proteins that have folded incorrectly.
The body’s power plant mitochondria. Credit: Istockphoto.
The misfolded proteins then clump together and form sticky, cell-damaging deposits called plaques.
“We know that mitochondria are at the centre of the aging process,” says Prof Nick Hoogenraad, executive director of the La Trobe Institute for Molecular Science (LIMS). Nick and his team have found a mechanism mitochondria use to remove the plaques that are prone to form as we age.
A Parkinson patient who can walk again, and improved life for people with the behavioural disorder known as Tourette syndrome.
Peter Silburn and his team are using deep brain stimulation to help movement and mood disorder patients beyond the reach of other therapies. Credit: Sunday Mail.
These are two of the results of a partnership between University of Queensland neurologist Prof Peter Silburn and neurosurgeon Dr Terry Coyne who have ventured deeper into the human brain than anyone else in the world.
Peter treats patients at St. Andrew’s Hospital in Brisbane using deep brain stimulation, a technique that uses electrodes to stimulate a region some 12 centimetres under the surface of the brain.
“There are 100 billion neurons in the brain and we can’t restore all of them. But the deep brain is like a telephone exchange—by stimulating this one section of the brain, you can unblock the flow of messages,” Peter says. Continue reading Parkinson answers deep in the brain→
What began decades ago as the discovery of an antibody from mice that targets human cancer cells is now undergoing human trials in the US as the basis of a treatment for acute leukaemia.
Professor Andrew Boyd, who has seen his antibody discovery incorporated into a potential cancer treatment. Credit: QIMRThe antibody targets a protein called EphA3, which is found in about half of all acute leukaemias as well as many other human cancers including a significant proportion of malignant melanomas, brain tumours and lung cancers. The antibody, called KB004, has been shown to kill certain types of cancerous tumours grown from human samples. Continue reading Life’s work closer to saving lives→
Imagine a future where recharging your tablet could be as easy as typing a tweet—where portable electronic devices power themselves without ever plugging into the grid.
Electricity is generated as a force is applied to a piezoelectric film. Credit: Dr Daniel J. WhiteResearchers at RMIT University, Melbourne have assessed the capacity of piezoelectric films—thin layers that turn mechanical pressure into electricity—to do this.
The study is the first to evaluate how piezoelectric thin films, a thousandth of a millimetre thick, perform at the molecular level, precisely measuring the level of electrical voltage and current—and therefore, power—that could be generated. Continue reading A step towards an everlasting battery→
A Flinders University chemist is using Australia’s OPAL research reactor at Lucas Heights in Sydney to investigate ancient Aboriginal Australian society.
Using the technique called neutron activation analysis, Dr Rachel Popelka-Filcoff can “geochemically fingerprint” Aboriginal ochre pigments from different locations, archaeological sites and artefacts. Rachel Popelka-Filcoff can trace the cultural use of ochre using Australia’s research reactor. Credit: Ashton Claridge, Flinders MediaAs the geochemical composition of ochre varies with location, she can correlate each sample with its site of origin, gaining information on cultural practices, travel and exchange patterns, and the relationship of Aboriginal people to the landscape. “Ochre pigments are highly significant in Aboriginal culture,” says Rachel. “Cultural expression often requires a specific pigment. Applying ochre to an object such as a spear can transform both its colour and its cultural meaning.”
Dr Roman Dronov, also from Flinders, is using the reactor to study the formation of bacterial protein layers. He is applying what he finds to constructing a new type of biosensor based on these layers and porous silicon. These highly sensitive devices can rapidly detect trace amounts of molecules, such as environmental poisons and markers of disease—a great improvement on traditional analytical methods. Continue reading OPAL reactor fingerprints Aboriginal ochre→
An Australian invention is making it cheaper, quicker and safer to manufacture the radioactive tracers used in latest medical imaging techniques to track down increasingly smaller clusters of cancer cells.
The two-step dual reactor, FlexLAB. Credit: iPHASE Technologies
Like preparing a cake in a mixing bowl, the chemical reactions to make the tracers involve putting the ingredients together in the right proportions. The next generation of tracers can have a more complex recipe—and so can be more difficult to produce using just one ‘mixing bowl’ at a time. Continue reading Two steps forward for cancer detection→
There’s a new diagnostic tool being developed to target melanoma, the deadly form of skin cancer with which more than 10,000 Australians are diagnosed each year.
The red arrows show a melanoma tumour. The PET/CT scan on the right shows how the MEL050 tracer highlights the location, size and spread of melanoma. Credit: Peter MacCallum Cancer Centre
It’s a chemical compound designed to highlight small traces of these cancer cells in the body.
Melanoma occurs when the cells that make melanin, the dark pigment normally found in the skin, become cancerous. Melanoma cells often spread elsewhere in the body before the primary tumours are detected and removed surgically. Clusters of these melanoma cells can be hard to detect before they grow into tumours by which time they are often incurable. Continue reading Unmasking melanoma early→
Researchers in the School of Geosciences at the University of Sydney have developed a computer package that lets scientists record and study the Earth over geological time.
GPlates image showing topography (left) and predicted temperature 300 km below surface (right) as India moves towards the Eurasian continent 60mya. Credit: Sabin Zahirovic, EarthByte
Their GPlates software, which they describe as “Google Earth with a time-slider,” contains powerful tools for modelling geological processes. Yet it is simple enough to use in schools or at home, and is freely available. By combining data on continental motion, fossils and sediments, for example, scientists can analyse changes in geography, ocean currents and climate over geological time. Continue reading Slide back in time and see the Himalayas form→
Australian engineers and physicists have developed a ‘single electron reader’, one of the key building blocks needed to make a quantum computer.
Andrew Dzurak (left), Andrea Morello and their colleagues have read the spin of a single electron. Credit: UNSWQuantum computers will use the spin, or magnetic orientation, of individual electrons for their calculations. And, because of the quantum nature of electrons, quantum computers could be exponentially faster at certain tasks than traditional computers.
In order to employ electron spin, a quantum computer needs both a way of changing the spin state (writing information) and of measuring that change (reading information). Together these two form a quantum bit or qubit – the equivalent of the bit in a conventional computer. Continue reading Computing with a single electron→
Hundreds of Aussie science achievements that you can share in speeches, posts and publications
