Tag Archives: diagnostics

Ultra-sensitive dengue detection

“Dengue has a significant impact on both Australia and Indonesia—the disease is hyper-endemic in Indonesia and affects the daily life of people living in the country,” says Dr Tedjo Sasmono of the Eijkman Institute for Molecular Biology in Jakarta.

Their researchers have been working with The University of Queensland to create a new way to screen blood for dengue virus.

It’s the result of a joint-research project on dengue diagnostics, initiated in 2015 and funded by an Australian Research Council (ARC) Linkage grant in collaboration with the Australian Red Cross Blood Service.

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Fibre optics: from cables to colon health

A new fibre optic medical tool is revolutionising our understanding of serious but socially embarrassing digestive illnesses, such as constipation, diarrhoea and irritable bowel syndrome. Thanks to this device, medical scientists can see for the first time the coordinated, fine and complex muscular activity of the human digestive system in action.


CSIRO optical physicist Dr John Arkwright, together with Dr Philip Dinning, of Flinders University, collected a 2011 Eureka Prize for their creation of the fibre optic catheter, which gleans information about digestive function by measuring pressure.
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Two steps forward for cancer detection

An Australian invention is making it cheaper, quicker and safer to manufacture the radioactive tracers used in latest medical imaging techniques to track down increasingly smaller clusters of cancer cells.

Two steps forward for cancer detection
The two-step dual reactor, FlexLAB. Credit: iPHASE Technologies

Like preparing a cake in a mixing bowl, the chemical reactions to make the tracers involve putting the ingredients together in the right proportions. The next generation of tracers can have a more complex recipe—and so can be more difficult to produce using just one ‘mixing bowl’ at a time.
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Unmasking melanoma early

There’s a new diagnostic tool being developed to target melanoma, the deadly form of skin cancer with which more than 10,000 Australians are diagnosed each year.

Unmasking melanoma early
The red arrows show a melanoma tumour. The PET/CT scan on the right shows how the MEL050 tracer highlights the location, size and spread of melanoma. Credit: Peter MacCallum Cancer Centre

It’s a chemical compound designed to highlight small traces of these cancer cells in the body.

Melanoma occurs when the cells that make melanin, the dark pigment normally found in the skin, become cancerous. Melanoma cells often spread elsewhere in the body before the primary tumours are detected and removed surgically. Clusters of these melanoma cells can be hard to detect before they grow into tumours by which time they are often incurable.
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Fresh Science 2010

Each year we identify early-career scientists with a discovery and bring them to Melbourne for a communication boot camp. Here are some of their stories.

More at www.freshscience.org.au

Print your own lasers, lights and TV screens

Print your own lasers, lights and TV screens
Jacek Jasieniak sprinkling quantum dots. Credit: Jacek Jasieniak

Imagine printing your own room lighting, lasers, or solar cells from inks you buy at the local newsagent. Jacek Jasieniak and colleagues at CSIRO, the University of Melbourne and the University of Padua in Italy, have developed liquid inks based on quantum dots that can be used to print such devices and in the first demonstration of their technology have produced tiny lasers. Quantum dots are made of semiconductor material grown as nanometre-sized crystals, around a millionth of a millimetre in diameter. The laser colour they produce can be selectively tuned by varying their size.

Cling wrap captures CO2
Colin Scholes operates a test rig for his carbon capture membrane. Credit: CO2 CRC

Cling wrap captures CO2

High tech cling wraps that ‘sieve out’ carbon dioxide from waste gases can help save the world, says Melbourne University chemical engineer, Colin Scholes who developed the technology. The membranes can be fitted to existing chimneys where they capture CO2 for removal and storage. Not only are the new membranes efficient, they are also relatively cheap to produce. They are already being tested on brown coal power stations in Victoria’s La Trobe Valley, Colin says. “We are hoping these membranes will cut emissions from power stations by up to 90 per cent.”

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Whiplash: who won’t get better?

MRI scan showing fat infiltration into neck muscle. Credit: James Elliot, University of Queensland
MRI scan showing fat infiltration into neck muscle. Credit: James Elliot, University of Queensland

Most people recover from whiplash injuries within the first few months. However, some people have long term pain—lasting months or years. Until now there has been no way of diagnosing these more severe cases.

New research suggests that fat deposits in the neck muscles are the key.

“We’ve found that people with long term injury have large amounts of fat infiltration in their neck muscles,” says Dr James Elliott from the University of Queensland (and former US professional baseball player). “Something is causing that difference, and it isn’t their body weight,” he says.

Tiny particles could assist in breast cancer screening

These optically barcoded nanoparticles could transform cancer diagnosis.
These optically barcoded nanoparticles could transform cancer diagnosis.

Blood tests using nanoparticles carrying molecules which can detect breast cancer biomarkers could save millions of lives and open the way to mass screening for many cancers.

Prof. Matt Trau, of the Australian Institute for Bioengineering & Nanotechnology at the University of Queensland, and his team are using a combination of nanotechnology and molecular biology in the project, funded by a five-year $5 million grant from the National Breast Cancer Foundation.

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Detecting aircraft fatigue

TanyaMonro_300x180The only way to find out whether the internal structures of an aircraft are corroded is to pull the plane apart and look. But new nanotechnology-based techniques being developed by Prof. Tanya Monro, Director of University of Adelaide’s Centre of Expertise in Photonics, in collaboration with the Defence Science and Technology Organisation, could make costly visual inspection in preventive aircraft maintenance a thing of the past.

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Know your enemy

ARCMicrobialGenomics_wheel-grass-sheepDiseases such as leptospirosis, fowl cholera, bovine respiratory diseases or footrot in sheep have devastating impacts on livestock industries worldwide. They have a debilitating effect on animals, leading to food shortage and major economic losses.

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