Fire fighters should identify what are potentially the worst-case events and prepare for them, even if they are extremely unlikely to occur, says Bushfire Cooperative Research Centre psychology researcher Claire Johnson.
Fire fighters need to be prepared for the worst that can happen. Credit: Queensland Fire and Rescue Service
“A failure to consider worst-case scenario possibilities has been implicated in a number of high-profile investigations into Australian bushfire disasters,” says Claire, who submitted her PhD thesis on worst-case scenario planning to La Trobe University in Melbourne in March this year.
For instance, the inquiries following the Canberra bushfires in 2003 and the Wangary fires on South Australia’s Eyre Peninsula in 2006 both suggested lack of considering the worst contributed to an underestimation of the threat posed. Continue reading Preparing for the worst→
New computer models are challenging the conventional wisdom in marine science.
Beth Fulton’s fisheries models are used all over the world. Credit: IstockphotoThese models have revealed for example that: large populations of jellyfish and squid indicate a marine ecosystem in trouble; not all fish populations increase when fishing is reduced—some species actually decline; and, sharks and tuna can use jellyfish as junk food to see them through lean periods.
The models were developed by the 2007 Science Minister’s Life Scientist of the Year, Dr Beth Fulton, a senior research scientist at CSIRO Marine and Atmospheric Research in Hobart. Continue reading Virtual management of the world’s oceans→
Physicist Dr Amanda Barnard has been using supercomputers to find the balance between sun protection and potential toxicity in a new generation of sunscreens which employ nanoparticles.
Dr Amanda Barnard with one of her nanoparticle simulations Credit: L’Oréal/SDP PhotoThe metal oxide nanoparticles which block solar radiation are so small they cannot be seen, so the sunscreen appears transparent. But if the particles are too small, they can produce toxic levels of free radicals.
Amanda, who heads CSIRO’s Virtual Nanoscience Laboratory, has been able to come up with a trade-off—the optimum size of particle to provide maximum UV protection for minimal toxicity while maintaining transparency—by modelling the relevant interactions on a supercomputer. Continue reading Saving our skins→
Dr Kate Trinajstic has used synchrotron light and CT scanning to see through rock, in the process discovering how ancient fish developed teeth, jaws and even a womb. Her work is increasing our understanding of how life on Earth evolved.
The winner of the 2010 Malcolm McIntosh Prize for Physical Scientist of the Year, Kate Trinajstic. Credit: Ron D’RaineAbout 380 million years ago in what is now the Kimberley Ranges in Western Australia, a vast barrier reef formed. In what would have been the inter-reef basins, large numbers of fish were buried relatively intact. Protective limestone balls formed around them and preserved them. When these balls are treated with acetic acid, the main component of vinegar, the surrounding rock dissolves, leaving only fossilised fish bones.
But in the course of studying hundreds of these dissolving balls, Kate began to see what looked like muscle fibres between the bones. She was eventually able to convince her colleagues that irreplaceable soft tissue detail was being lost in the acid treatments. Continue reading Seeing fish through rocks→
A Flinders University chemist is using Australia’s OPAL research reactor at Lucas Heights in Sydney to investigate ancient Aboriginal Australian society.
Using the technique called neutron activation analysis, Dr Rachel Popelka-Filcoff can “geochemically fingerprint” Aboriginal ochre pigments from different locations, archaeological sites and artefacts. Rachel Popelka-Filcoff can trace the cultural use of ochre using Australia’s research reactor. Credit: Ashton Claridge, Flinders MediaAs the geochemical composition of ochre varies with location, she can correlate each sample with its site of origin, gaining information on cultural practices, travel and exchange patterns, and the relationship of Aboriginal people to the landscape. “Ochre pigments are highly significant in Aboriginal culture,” says Rachel. “Cultural expression often requires a specific pigment. Applying ochre to an object such as a spear can transform both its colour and its cultural meaning.”
Dr Roman Dronov, also from Flinders, is using the reactor to study the formation of bacterial protein layers. He is applying what he finds to constructing a new type of biosensor based on these layers and porous silicon. These highly sensitive devices can rapidly detect trace amounts of molecules, such as environmental poisons and markers of disease—a great improvement on traditional analytical methods. Continue reading OPAL reactor fingerprints Aboriginal ochre→
Donor corneas conditioned with DNA before being transplanted into new eyes are already actively contributing to their own success in experimental animals such as sheep.
An Australian research group is making corneal transplant easier. Credit: iStockphotoThe DNA is inserted into the cells of the cornea after it has been harvested. Then, following implantation, it produces proteins that help overcome immunological rejection.
This is one of many strands of research aimed at increasing the success rates of corneal transplants and other eye disease treatments undertaken by Prof Keryn Williams at Flinders University. Continue reading Helping eyes to help themselves→
We know more about the topography of Mars than that of Earth because 70 per cent of our planet is covered by water.
Kara Matthews has mapped the seafloor using satellite data and software. Credit: Kara Matthews
Now University of Sydney PhD student Kara Matthews has used satellite data and GPlates, a computer package developed at the University, to create a complete digital map of the many geological features of the seafloor.
Fracture zones—the orange lines in the accompanying image—are deep linear scars on the seafloor that extend perpendicular to the boundaries where tectonic plates are moving apart, revealing up to 150 million years of plate movement. They are accompanied by huge ridges on the seafloor, rising up to 2 km above the abyssal plains, and valleys as deep as 8 km below sea level. Continue reading Mapping the seafloor from space→
Absorbing carbon emissions from power stations and creating a new generation of hydrogen fuel tanks in future vehicles are just some of the potential applications of Dr Deanna D’Alessandro’s discoveries in basic chemistry.
She has created new, incredibly absorbent chemicals that can capture, store and release large volumes of gas.
It’s all to do with surface area, says Deanna, a postdoctoral research fellow in the School of Chemistry at The University of Sydney.
She has constructed crystals that are full of minute holes.
One teaspoon of the most effective of these compounds has the surface area of a rugby field.
What’s more, the size and shape of the pores can be customised and changed using light. So she believes she can generate molecular sponges that will mop up carbon dioxide, hydrogen, or in theory almost any gas—and then release it on cue.
In 2010, her achievements won her a $20,000 L’Oréal Australia For Women in Science Fellowship which provided equipment, travel support and a student to assist her.
Deanna’s compounds have similar molecular structures to those in seashells and the microscopic marine plants called diatoms.
These naturally-occurring materials are commonly used in toothpaste, laundry detergents, kitty litter and other industrial applications.
But her high tech equivalents are crystals known as metal-organic frameworks—clusters of charged metal atoms linked by carbon-based groups.
While she didn’t invent these frameworks, Deanna has developed new kinds of them which are more robust and possess the molecular pores that can be shaped by light.
Photo: Deanna D’Alessandro, The University of Sydney. Credit: L’Oréal Australia/SDP media
School of Chemistry, The University of Sydney, Deanna D’Alessandro, Tel: +61 2 9351 7392, deanna@chem.usyd.edu.au, scienceinpublic.com.au/loreal
Some of the biochemical tricks the malaria parasite uses to become resistant have been unravelled thanks to a series of discoveries by Dr Rowena Martin and her colleagues at the Australian National University.
She is using those insights to give a new lease of life to chloroquine, the wonder drug against malaria first discovered in the 1950s.
For more than half a century chloroquine saved hundreds of millions of lives, but now chloroquine-resistant malaria strains have become common in developing countries.
Rowena is working to understand what happened. The single-celled malaria parasite enters our bodies when we are bitten by an infected mosquito.
It eventually invades and plunders our red blood cells, consuming the haemoglobin contained within.
The digestion of haemoglobin, which takes place in the parasite’s stomach compartment, releases the iron-containing, nonprotein component, haem.
Free haem is toxic to the parasite, which responds by converting it to a harmless crystal. Chloroquine works by blocking the formation of these crystals.
Ten years ago researchers discovered that just a few small changes in a protein PfCRT were enough to give the parasite resistance to chloroquine. But they did not know what the changes did.
Rowena developed a system to study PfCRT in frog eggs—allowing her to examine it in isolation and in detail.
“We found that it moves chloroquine out of the parasite’s stomach compartment so that the drug can’t accumulate at its site of action.” For her achievements to date, in 2010 Rowena won a $20,000 L’Oréal Australia For Women in Science Fellowship.
Photo: Rowena Martin, the Australian National University, Canberra/The University of Melbourne. Credit: L’oréal Australia/SDP media.
Research School of Biology, The Australian National University, Rowena Martin, Tel: +61 2 6125 8589, Rowena.Martin@anu.edu.au, www.scienceinpublic.com.au/loreal
Mystery still surrounds why women who recover from breast cancer often relapse years later —Dr Marie-Liesse Asselin-Labat is hoping to use her knowledge of breast tissue stem cells to unravel it.
In 2006, she was part of the Walter and Eliza Hall Institute team that discovered breast stem cells.
She then built on this finding with a series of studies exploring how these cells develop and are influenced by oestrogen and other steroids.
Her achievements won her a $20,000 L’Oréal Australia For Women in Science Fellowship in 2010. Breast stem cells are critical to normal breast development, but if the breast becomes cancerous they are also likely to be at heart of the problem.
And that’s been the focus of Marie- Liesse’s work. In a series of high impact papers working with mice, she has explored how these breast stem cells develop into the wide range of cells found in a normal breast and how some of them become aggressive cancer cells.
In 2010 she was lead author of a Nature paper revealing that oestrogen and other steroids can control the function of breast stem cells. “It’s via an indirect mechanism important in understanding how stem cells proliferate, and it could lead to new treatments and new drugs,” she says. “But there are basic questions we still need to answer about breast cancer—such as, ‘What is the cell of origin?’ and ‘What causes a cell to go wrong and turn to cancer?’”
