Genetics guiding anxiety treatment

For years we’ve been identifying genetic markers linked to mental disorders. Now it appears those same markers could also tell us who will best-respond to treatment.

Genetic data are another piece in the puzzle of personalised treatment for anxiety. Credit: Chris Stacey, Macquarie University
Genetic data are another piece in the puzzle of personalised treatment for anxiety. Credit: Chris Stacey, Macquarie University

A study of over 1,500 children, as part of the international Genes for Treatment collaboration, found those with a specific genetic marker were more responsive to psychological therapy than those without.

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Building an emotionally healthy community

A unique national centre is working to build an emotionally healthy community through science and practice.

From four-year-olds with anxiety, to 90-years-olds with depression, the Centre for Emotional Health at Macquarie University takes a ‘lifespan approach’ to mental health.

They’ve spent the past 20 years studying, developing, testing and rolling out mental health programs – which are now available in eight languages and 15 countries including Denmark, the UK and Norway.

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Towards the first quantum computer – in silicon

Across the world, the race is on to develop the first quantum computer and an Australia research centre is at the front of the pack.

The Australian Government, Telstra and the Commonwealth Bank of Australia have recently recognised the pole position of the ARC Centre of Excellence for Quantum Computation and Communication Technology (CQC2T) by investing $46 million towards a targeted goal of realising a 10-qubit quantum integrated circuit in silicon within the next five years.

In this feature we explore some of the Centre’s advances in quantum information research.

For more information:
Centre for Quantum Computation and Communication Technology
Tony Raeside
tony.raeside@unsw.edu.au

Geoffrey Rush talks stars

The search for the first stars and the hunt for dark energy both feature in a new planetarium show narrated by Geoffrey Rush. The show premiered in March 2016 at the Melbourne Planetarium and will be seen in planetariums around the world.

“I hope this show conveys some of the wonder of the Universe we live in,” says Professor Elaine Sadler, Director of the ARC Centre of Excellence for All-sky Astrophysics (CAASTRO).

The Murchison Widefield Array telescope is discovering when the first stars and galaxies formed.
The Murchison Widefield Array telescope is discovering when the first stars and galaxies formed
Credit: Alex Cherney/Museum Victoria

‘Capturing the Cosmos’ was created by Melbourne Planetarium and CAASTRO, and features the work of two of Australia’s new telescopes, the Murchison Widefield Array and Skymapper.

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Maths to answer big questions (it’s not always 42)

Many of today’s big questions can only be answered with new mathematical and statistical tools.

That’s what the ARC Centre of Excellence for Mathematical and Statistical Frontiers are working on, and they’re finding real-world applications in areas as diverse as:

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Trillions of bubbles at work for Australia

Graeme Jameson’s technologies use trillions of bubbles to add billions of dollars to the value of Australia’s mineral and energy industries.

Graeme took flotation, a century-old technology developed in Broken Hill, and transformed it. A turbulent cloud of minute bubbles are pushed through a slurry of ground-up ore where they pick up tiny mineral particles and carry them to the surface.

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Indonesian and Australian scientists test new TB vaccine targets

Better vaccines are needed for the global fight against tuberculosis (TB). The Global Fund reports an estimated nine million new cases globally per year of TB, which is second only to AIDS as the world’s most deadly infectious disease.

Indonesia had more than 320,000 reported cases in 2014 according to the World Health Organization, while Australia’s reported cases were just over 1,000. But the rise of drug-resistant TB poses a threat to all countries.

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Filtering the blood to keep cancer in check

A new diagnostic system used to detect cancer cells in small blood samples could next be turned towards filtering a patient’s entire system to remove those dangerous cells – like a dialysis machine for cancer – says an Australian researcher who helped develop the system.

The technique was developed for cancer diagnosis, and is capable of detecting (and removing) a tiny handful of cancer-spreading cells from amongst the billions of healthy cells in a small blood sample.

The revolutionary system, which works to diagnose cancer at a tenth of the cost of competing technologies, is now in clinical trials in the US, UK, Singapore and Australia, and is in the process of being commercialised by Clearbridge BioMedics PteLtd in Singapore.

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The short lives of hard-living, fast burning, high mass stars

2015 L'Oréal-UNESCO For Women in Science Fellow Shari Breen (Credit: L'Oréal Australia) Dr Shari Breen, astronomer, CSIRO, Sydney

We are made of star stuff. The nitrogen in our DNA, the calcium in our teeth and the iron in our blood were all made in high mass stars that burnt briefly and brightly before exploding.

Dr Shari Breen is using ‘The Dish’ at Parkes and a network of international telescopes to understand the life cycle and evolution of these stars. For her the 1,000 tonne Parkes radio telescope is an old friend that creaks and grumbles as she guides it across the sky, hunting for high mass stars.

She will use her L’Oréal-UNESCO For Women in Science Fellowship to develop her use of masers (laser-like beams of intense radio waves) to investigate these stars.

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How we imagine the future

Dr Muireann Irish, cognitive neuroscientist, Neuroscience Research Australia/UNSW, Sydney

2015 L'Oréal-UNESCO For Women in Science Fellow Muireann Irish (Credit: L'Oréal Australia) Dr Muireann Irish has discovered which parts of our brain are essential to imagine the future, ranging from simple things like “I must remember my keys and my wallet when I go out,” to imagining complex events such as “my next holiday”. And she has shown that people with dementia don’t just lose the ability to remember the past, they also lose the ability to envisage the future.

She will use her L’Oréal-UNESCO For Women in Science Fellowship to better understand how dementia affects this cognitive function. She expects her work will inform the development of activities for patients that will improve their quality of life and reduce the burden faced by caregivers.

Cognitive decline in the form of dementia will be one of the greatest challenges for our health system in the next fifty years and Muireann is leading the search for solutions.

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