Category Archives: 2015

Finding new drugs for malaria

New drugs may be on the way for malaria, a disease that helps push millions of people into extreme poverty, thanks to an Australian team working with a remarkable new Japanese organisation.

Continue reading Finding new drugs for malaria

Could your lab have the next antibiotic?

Could your newly synthesised molecule kill a superbug? Matt Cooper can tell you.

His team is offering a free screening service for the world’s chemists to test their compounds against antibiotic-resistant bacteria, helping them to potentially find a new antibiotic that will fight the rise of these ‘superbugs’.

“We’re helping the community unlock the hidden value of these chemicals,” says Matt, whose team is from the Community for Open Antimicrobial Drug Discovery (CO-ADD), a not-for-profit, global initiative of The University of Queensland’s Institute for Molecular Bioscience. The screening began in February 2015, and Matt has already received thousands of samples from locations including India, Singapore, New Zealand, France, Israel, UK and the USA.

Continue reading Could your lab have the next antibiotic?

Australian crystals clean gas, food, air…

Forty per cent of the energy consumed by industry is used to separate things— in natural gas production, mineral processing, food production, pollution control. The list goes on.

Matthew Hill’s crystals will save energy across industry. Credit: Prime Minister’s Prizes for Science/WildBear
Matthew Hill’s crystals will save energy across industry. Credit: Prime Minister’s Prizes for Science/WildBear

Each offers an application for Matthew Hill’s crystals. He has demonstrated that the space inside metal–organic frameworks (MOFs)—the world’s most porous materials—can be used as efficient and long-lasting filters.

By choosing different combinations of metals and plastics, Matthew’s CSIRO team can make a wide range of customised crystals. Then, using antimatter and synchrotron light, they map the internal pores, determine what each crystal can do and explore potential applications.

Continue reading Australian crystals clean gas, food, air…

The genetics of epilepsy: bringing hope to families

Sam Berkovic and Ingrid Scheffer have changed the way the world thinks about epilepsy, a debilitating condition that affects about 50 million people.

The Hon Tony Abbott, PM, with recipients of the 2014 Prizes, credit: Prime Minister’s Prizes for Science; Ingrid Scheffer and Sam Berkovic revealed the underlying genetic element of many epilepsies. Credit: Prime Minister’s Prizes for Science/WildBear
The Hon Tony Abbott, PM, with recipients of the 2014 Prizes, credit: Prime Minister’s Prizes for Science; Ingrid Scheffer and Sam Berkovic revealed the underlying genetic element
of many epilepsies. Credit: Prime Minister’s Prizes for Science/WildBear

Twenty years ago doctors tended to regard most forms of epilepsy as acquired rather than inherited. In other words, they believed epilepsy was mostly due to injury: the result of things like a crack on the head in a car accident, a bad fall in the playground, a tumour, or something having gone wrong in labour. Parents felt responsible and the resulting guilt was enormous.

The two clinician-researchers from The University of Melbourne have led the way in finding a genetic basis for many epilepsies, building on their discovery of the first ever link between a specific gene and a form of epilepsy. Finding that answer has been of profound importance for families.

Along the way, Sam and Ingrid discovered that a particularly severe form of epilepsy, thought to result from vaccination, was actually caused by a gene mutation. This finding dispelled significant concerns about immunisation.

Continue reading The genetics of epilepsy: bringing hope to families