All posts by Operations

Birds, bees, robots and flying

He isn’t a pilot, but few people would know more about ways of navigating while flying than Prof Mandyam Srinivasan (Srini) of the Queensland Brain Institute. And he’s steadily finding out more.

Srinivasan works on bee navigation: here he is in the All-Weather Bee Flight Facility at the Queensland Brain Institute (QBI) Credit: Dee McGrath/QBI
Srinivasan works on bee navigation: here he is in the All-Weather Bee Flight Facility at the Queensland Brain Institute (QBI). Credit: Dee McGrath/QBI

Initially known for his work in bees, since receiving the Prime Minister’s Prize for Science in 2006, Srini has shown that birds and insects use a similar system of visual guidance to prevent themselves from crashing into trees when flying through dense forest.

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Galactic shutterbug

A new instrument at the Australian Astronomical Observatory (AAO) can sample the light coming from hundreds of galaxies per night—which can tell us new things about the universe.

Astronomer Sam Richards sitting in the prime focus cage at the Anglo-Australian Telescope, where the SAMI instrument usually sits. Credit: Jon Lawrence
Astronomer Sam Richards sitting in the prime focus cage at the Anglo-Australian Telescope, where the SAMI instrument usually sits. Credit: Jon Lawrence

Sydney-AAO Multi-object Integral field spectrograph (SAMI) can look at up to 100 galaxies in a night, because it can look at 60 different regions in each of 13 different galaxies, all at once.

But most observatories around the world can only do one galaxy at a time.
Continue reading Galactic shutterbug

Intelligent drugs

Dr Georgina Such imagines a miniscule capsule designed like a set of Russian babushka dolls.

Georgina Such is working on smart capsules could change the way we deliver drugs. Credit: L’Oréal Australia/sdpmedia.com.au
Georgina Such is working on smart capsules could change the way we deliver drugs. Credit: L’Oréal Australia/sdpmedia.com.au

The capsule is designed to sneak through the blood stream untouched.

When it finds its target—a cancer cell—it passes into the cell, sheds a layer, finds the part of the cellular machinery it needs to attack, sheds another layer; and then releases its cargo of drugs, destroying the cancer cell and only the cancer cell.

Creating such a capsule may take decades, but Georgina and her colleagues at the University of Melbourne have already developed several materials which have the potential to do the job.

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Supercomputer probes cancer crisis point

The long-term survival chances of patients with breast cancer plummet if the cancer recurs or spreads to other parts of the body in the process known as metastasis.

Breast cancer cells visualised with antibodies recognising E-cadherin (red) or vimentin (green). The cell nuclei are visualised with a DNA-binding stain (blue). Credit: Cletus Pinto & Rhiannon Coulson, St Vincent’s Institute

So the National Breast Cancer Foundation recently funded a five-year, $5 million National Collaborative Research Program to investigate metastasis and discover potential drugs to stop or slow it. The EMPathy Breast Cancer Network program was also charged with finding ways of diagnosing metastasis before it occurs. The research is highly dependent on the latest sequencing technology and demands the massive computer power and sophisticated data handling techniques of modern bioinformatics.
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Tracking lithium for better batteries

Imagine a mobile phone, gaming gadget or laptop with a battery that never needs replacing, or electric cars powered by batteries that are as fast to recharge as it is to refill your car with petrol.

Neeraj Sharma prepares a sample battery in the glove box. Credit: ANSTO
Neeraj Sharma prepares a sample battery in the glove box. Credit: ANSTO

Researchers at the Australian Nuclear Science and Technology Organisation (ANSTO) are unlocking the secret inner workings of lithium ion (Li-ion) batteries to develop better, safer portable power.
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Australian science’s place in Asia

Australia’s scientists are among the most productive in the region. That’s the picture that emerges from the Nature Publishing Index 2011 Asia-Pacific released in March 2012

AUSTRALIA RANKS THIRD IN THE ASIA-PACIFIC REGION IN TERMS OF PUBLICATIONS IN NATURE GROUP JOURNALS. CREDIT: NASA VISIBLEEARTH.NASA.GOV

Australia ranks second only to Singapore in terms of science output per capita and per scientist in the Index, which measures the publication of research articles in Nature research journals by Asia-Pacific nations and institutions. Singapore and Australia are also first and second in the Asia-Pacific respectively in terms of GDP per capita. Continue reading Australian science’s place in Asia

Star-shaped polymers boost engine performance

New lubricants containing star-shaped polymers have hit the market, thanks to Australian polymer technology. Lubrizol Corporation has launched the first commercial products developed using CSIRO’s Reversible Addition Fragmentation chain Transfer (RAFT) polymer synthesis process.

Asteric ™ Viscosity Modifiers are tailor-made star-shaped polymers made possible by RAFT Credit: Lubrizol
Asteric ™ Viscosity Modifiers are tailor-made star-shaped polymers made possible by RAFT Credit: Lubrizol

CSIRO chemist Dr Ezio Rizzardo says the RAFT process allows much greater flexibility and potential for polymer synthesis, compared with conventional methods. “Conventional polymerisation is a relatively simple process with two ingredients: large amounts of monomer and a small amount of an initiating agent. You apply heat; a chain reaction starts and runs to completion, making polymer chains that can have widely varying lengths.”
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New chlorophyll a gateway to better crops

A chance finding has led to the first new chlorophyll discovered in 67 years, opening up possibilities for biofuel and food crops to use sunlight more efficiently.

2011 Life Scientist of the Year Min Chen. Credit: Prime Minister's Science Prizes/Bearcage
2011 Life Scientist of the Year Min Chen. Credit: Prime Minister’s Science Prizes/Bearcage

Continue reading New chlorophyll a gateway to better crops

New tool for better breast cancer detection

Queensland scientists are helping radiologists to spot the more subtle signs of breast cancer, using computer tools and magnetic resonance imaging (MRI).

Photo: Contrast-enhanced MRI of a breast. Credit: Yaniv Gal
Photo: Contrast-enhanced MRI of a breast. Credit: Yaniv Gal

Currently MRI allows radiologists to detect lumps or other growths by creating a 3D anatomical image of the breast.

Prof Stuart Crozier and his team at the University of Queensland have developed a computer tool that improves MRI detection by spotting more subtle indicators of cancer.

“When cancers are just starting to form, they form abnormal blood vessels very early, to feed their rapid cell division,” Stuart says.

“By seeing how certain contrast agents move through the tissue, we can pick up the formation of these blood vessels.”

Photo: Research Assistant Michael Wildermoth works with the software that shows how certain contrast agents move through breast tissue. Credit: Kim Nunes
Photo: Research Assistant Michael Wildermoth works with the software that shows how certain contrast agents move through breast tissue. Credit: Kim Nunes

This works towards solving two issues with conventional MRIs.

First, it should reduce the number of false positive results and therefore the number of women put through biopsies of benign tumours.

Second, this should catch tumours earlier, not just when tumours are big enough to discern visually.

“The goal is to assist radiologists to identify areas of cancer risk that may not be obvious on conventional images,” Stuart says.

Stuart, a Fellow of the Australian Academy for Technological Sciences and Engineering (ATSE), was recently presented with a 2012 Clunies Ross Award for his contributions to the engineering of magnetic resonance imaging (MRI) technology.

The research, funded as an Australian Research Council’s Discovery Project, is now undergoing trials with 140 women at private radiology firm Queensland X-ray.

Photo: Contrast-enhanced MRI of a breast.
Credit: Yaniv Gal
Photo: Research Assistant Michael Wildermoth works with the software that shows how certain contrast agents move through breast tissue.
Credit: Kim Nunes

University of Queensland, Stuart Crozier, stuart@itee.uq.edu.au, www.itee.uq.edu.au

Massive galaxy survey confirms accelerating Universe

The Universe is definitely getting bigger, faster—and astronomers using the Anglo-Australian Telescope in NSW have confirmed it.

The WiggleZ survey looked at over 200,000 visible galaxies (middle), but also gave insights into dark matter (the green grid that deforms the gravity field) and dark energy (the purple grid). Credit: NASA/JPL-Caltech
The WiggleZ survey looked at over 200,000 visible galaxies (centre), but also gave insights into dark matter (the green grid that deforms the gravity field) and dark energy (the purple grid). Credit: NASA/JPL-Caltec

The results are now in for WiggleZ, a survey of the night sky, spanning 200,000 galaxies and billions of years of cosmic history.

“This puts a nail in it. Clearly the universe is accelerating, and clearly there is something like dark energy,” says Prof Matthew Colless, director of the Australian Astronomical Observatory and a member of the WiggleZ team.
Continue reading Massive galaxy survey confirms accelerating Universe