All posts by Michael Lucy

Tomorrow’s medicine starts today – Stem Cells Australia

Since its creation in 2011, the Stem Cells Australia initiative has increased our understanding of how to control and use stem cells in research. Our members have placed Australia at the forefront of stem cell medicine, and now we are developing new diagnostic, therapeutic and biological applications that will transform healthcare in the years and decades ahead.

Today, Stem Cells Australia members are:

Our researchers are learning about how the heart forms so they can identify drugs to stimulate heart repair and improve function; they are analysing big data to predict how cells behave and create custom immune cells; they are helping patients with damaged corneas see again using grafts made from their own stem cells; and much more.

Many of these achievements rely on large interdisciplinary teams from across Australia. Continue reading Tomorrow’s medicine starts today – Stem Cells Australia

Micro-lenses bring new cataract treatments in sight

Stem cells are being used to rapidly test and improve treatments for cataracts, thanks to an innovative solution developed by Dr Michael O’Connor and his team from Western Sydney University.

With novel stem cell technology, Michael has created hundreds of thousands of micro-lenses similar to the ones in the human eye. These micro-lenses offer a way to rapidly improve drug research and offer the potential for lens cell transplants in the future. 

Billions of dollars are spent each year around the world on cataract surgery, and hundreds of millions of dollars treating resulting complications. Continue reading Micro-lenses bring new cataract treatments in sight

How reprogramming cells turns back time

For the past decade scientists have been able to reprogram skin cells, nasal cells and other mature cells to become pluripotent stem cells that can turn into any cell type in the human body. How it works is only starting to become clear.

Teams led by Professors Ryan Lister at the University of Western Australia, Jose Polo at Monash University and Ernst Wolvetang at The University of Queensland are working together to understand how this process occurs, whether all cell types follow the same path to becoming pluripotent cells, and if this impacts their ability to mimic disease in the laboratory.

Through a series of collaborations over the last ten years the scientists have uncovered a number of stem cell secrets, opening the door for more targeted research and, ultimately, treatments for diseases. Continue reading How reprogramming cells turns back time

Building tools for brain repair

Professor James Bourne and his team are laying the groundwork for using stem cell transplants to treat brain trauma with the discovery of an anti-scarring agent and new biomaterials to support transplanted cells.

“What we’re doing is a prelude to direct stem cell research. We hope to give potential stem cell therapies for brain trauma the best chance of success,” James says.

He and his team at the Australian Regenerative Medicine Institute at Monash University are studying nonhuman primates to understand how to create the best environments for repair after brain injury. Continue reading Building tools for brain repair

“Who will help me?”

People suffering from serious illnesses are turning to unproven and risky stem cell therapies in growing numbers. Researchers are trying to understand why—and how to provide better information and support.

Stem cells have been saving lives for decades, largely through bone marrow and cord blood transplants treating leukaemia and other blood diseases. Unproven treatments are booming, however, with clinics in Australia and around the world spruiking cures for conditions from osteoarthritis and MS to dementia and diabetes.

Associate Professor Megan Munsie and her colleagues in Stem Cells Australia’s Engagement, Ethics and Policy Program have heard many tales of patients spending thousands of dollars on treatments that often have no benefit and may be harmful or even deadly. Continue reading “Who will help me?”

Mini-kidneys tell two sides of a genetic story

Gene editing technology combined with stem cells provides a powerful new way to study genetic kidney diseases and their treatments.

Melbourne researchers have used mini-kidney ‘organoids’ grown in the lab to unravel the mystery of why Mainzer-Saldino syndrome, a rare disease involving a single defective gene, causes life-threatening kidney damage. In doing so, they’ve proven an approach that can be used to study a whole range of other genetic kidney diseases. Continue reading Mini-kidneys tell two sides of a genetic story

Stories of French-Australian Innovation

Magazine cover of Stories of French-Australian Innovation
View the book as a PDF here.

Changing lives together: from water to astronomy to cancer, this collection showcases outstanding collaborations

between French and Australian researchers.

Scientific collaboration between Australia and France stretches back to the early days of European settlement, when La Pérouse built an observatory at Botany Bay in 1788.

Continue reading Stories of French-Australian Innovation

Wheat that’s good for guts

A new kind of wheat high in resistant starch can improve intestinal health

Bowel cancer is the world’s third most common cancer. A diet that includes more resistant starch, a kind of fibre that feeds good bacteria in the large intestine, can make it less common. Resistant starch helps improve gut health and reduces the risk of conditions such as diabetes, obesity, heart disease and cancer.

Since 2006, CSIRO scientists have been working in a joint venture with French company Limagrain Céréales Ingrédients and the Grains Research and Development Corporation to develop wheat with more resistant starch. Continue reading Wheat that’s good for guts

Reef rescue

French and Australian scientists are working together to understand how climate change is affecting reef sharks in French Polynesia, why corals in New Caledonia can survive extremes of temperature and acidity, and what fish markets mean for reef health.

Baby sharks

On Mo’orea in French Polynesia, Dr Jodie Rummer leads a project studying baby sharks to see how they will cope with climate change.

“Healthy reefs need healthy predators,” Jodie says. “And healthy predators need healthy reefs.” Continue reading Reef rescue

L’Astrolabe opens up Antarctica

For French and Australian explorers

Without the help of icebreaking ships, all-terrain vehicles and tough machinery, most Antarctic science could not happen. The French ship L’Astrolabe is a crucial facility for scientists exploring the Earth’s climate, oceans, atmosphere and ecology.

Every year, the ship and its crew, managed by the French Navy for the Institut polaire français Paul-Émile Victor (IPEV) from Hobart, support approximately 50 French and international scientific projects based out of the French stations Dumont d’Urville and Concordia. L’Astrolabe also transports food, supplies, logistics officers and scientists to and from the Australian Antarctic Division’s base on Macquarie Island.

Continue reading L’Astrolabe opens up Antarctica