A typhoid outbreak in Kathmandu has provided new insights into bacterial epidemics and antibiotic resistance, thanks to a Melbourne scientist’s genomic research.
Kathryn Holt, of the University of Melbourne’s Bio21 Institute, used genome sequencing to discover that an epidemic of deadly typhoid bacteria in Nepal’s capital city was driven by climate, and not by the outbreak of novel genetic strains.
Her research, published in the Royal Society journal Open Biology, changes our understanding of how typhoid spreads and how we can better respond to other bacterial epidemics.
Bearded dragons are revealing some of the secrets behind their colour-changing ways, thanks to the work of a Melbourne evolutionary scientist.
Devi Stuart-Fox with a bearded dragon. Credit: L’Oréal Australia/sdpmedia.com.au
Devi Stuart-Fox has discovered that bearded dragons change colour in response to heat, allowing them to regulate their body temperature.
Her research opens the way for scientists to imitate lizards and develop materials that respond to light and temperature for solar energy, sensor and biomedical applications.
Large numbers of premature-born children may be slipping under the radar, say researchers who have found brain development problems in teenagers deemed clinically normal after a late preterm birth.
Children born even one to five weeks premature can show reduced skills later in life.
Julia Pitcher and Michael Ridding, of the Robinson Research Institute, University of Adelaide, found that children born even one to five weeks premature showed reduced ‘neuroplasticity’ as teenagers. Their study provides the first physiological evidence of the link between late preterm birth and reduced motor, learning and social skills in later life.
Fifty million children in the world’s poorest countries will be vaccinated against the deadly rotavirus by 2015, thanks to the breakthrough work of a quiet Melbourne researcher.
Ruth Bishop. Credit: Stepping Stone Pictures
Ruth Bishop’s rotavirus discovery led to the development of the vaccine currently being rolled out by the Global Alliance for Vaccines and Immunisation—and to her declaration as 2013 CSL Florey Medal winner.
Each year, around half a million children die from rotavirus infection and the acute gastroenteritis it causes.
Coastal land clearing has led to poor water quality in the Great Barrier Reef lagoon and threats to reef animals, according to the first data providing evidence of the damage.
Land clearing and acidification threaten the Great Barrier Reef.
The Water Quality and Ecosystem Health research team at the Australian Institute of Marine Science has collected 20 years of data, which shows the connection between high rates of land clearing and reduced reef water quality in the late 1990s and early 2000s.
“Our analyses show that water quality in the lagoon dropped significantly during the late 1990s and early 2000s, a period that coincided with very high rates of vegetation clearing on land adjacent to rivers,” says research team leader, Britta Schaffelke.
Nanoscale spikes on dragonfly wings are inspiring materials that kill bacteria, including deadly antibiotic-resistant golden staph (Staphylococcus aureus).
Wandering percher dragonfly, Diplacodes bipunctata. Credit: Jean, via Encyclopedia of Life (CC BY-NC)
Elena Ivanova and her fellow researchers at Swinburne University of Technology were studying self-cleaning surfaces in nature when they discovered bacteria being killed on the wings of the clanger cicada, Psaltoda claripennis, a species mostly found in Queensland.
The secret seemed to lie in millions of tiny rounded spikes, or nanopillars, each a thousand times smaller than the width of a human hair.
Sea snails and sponges are shedding light on how to create electronic-free circuitry and environmentally friendly optical fibre, say Geelong scientists.
The structure of a sea snail’s mother-of-pearl layer suggests how to channel light.
Inspired by the materials these sea creatures make, an Australian-US team is trying to create 3D gold nanoparticle arrays that channel light.
“Effectively we are creating circuitry without electronics,” says Tiffany Walsh, Veski Innovation Fellow and one of the researchers from Deakin University.
Children with a deadly muscle-wasting disease are regaining the ability to walk and potentially avoiding life-threatening complications, thanks to a new treatment developed by researchers at Perth’s Murdoch University.
Photo: Steve Wilton and Sue Fletcher’s drug therapy is helping children who suffer from Duchenne muscular dystrophy stay active. Credit: Murdoch University
Dr Joanne (Jo) Whittaker, Institute for Marine and Antarctic Studies, University of Tasmania, Hobart
Dr Joanne (Jo) Whittaker likes to solve jigsaw puzzles. Now this marine geoscientist is tackling the biggest puzzle on the planet—the formation of continents.
With the help of Australia’s national marine research vessels, and now her L’Oréal Fellowship, Jo is reconstructing how the Indian, Australian and Antarctic tectonic plates separated over the past 200 million years, forming the Indian Ocean and the continents as we see them today. This information will help us model climate change better, find new gas resources, and understand the dynamics of the land in which we live.
The piece of this jigsaw she is now working on centres on two underwater plateaux, the Batavia and Gulden Draak Knolls, towering about 3000 metres above the Perth Abyssal Plain (PAP), which is around 1600 kilometres off the coast of Geraldton in Western Australia. In November 2011, Jo’s team mapped and sampled rocks from both knolls. Based on the evidence so far, Jo says, it looks like they split from the margins of the moving Indian Plate about 100 million years ago. Continue reading How Australia and India broke up—100 million years ago→
Dr Misty Jenkins, Peter MacCallum Cancer Centre, Melbourne
Dr Misty Jenkins spends a lot of her time watching killers at work: the white blood cells of the body that eliminate infected and cancerous cells. She can already tell you a great deal about how they develop into assassins and arm themselves. Now with the support of her L’Oréal For Women in Science Fellowship Misty is exploring how they become efficient serial killers—killing one cancer cell in minutes and moving on to hunt down others. Her work will give us a greater understanding of our immune system and open the way to better manage T cells to defeat disease.
Misty’s career so far has been quite a journey for a girl from Ballarat. Along the way she been mentored by Nobel Prize-winning immunologist Prof Peter Doherty and become the first Indigenous Australian to attend either Oxford or Cambridge. Now working with Prof Joe Trapani as a National Health and Medical Research Council (NHMRC) postdoctoral fellow in the Cancer Cell Death laboratory at the Peter MacCallum Cancer Centre in Melbourne, Misty has been awarded a $25,000 L’Oréal Australia and New Zealand For Women in Science Fellowship. She will use the money to further her study of what triggers T cells to detach themselves from their targets and seek additional prey. Continue reading When killing saves lives: our immune system at work→
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