New targets for tuberculosis vaccine

Better vaccines are needed for the global fight against tuberculosis (TB) with nine million new cases annually. Indonesia had more than 320,000 reported cases in 2014, while Australia’s reported cases were just over 1,000. But the rise of drug-resistant TB poses a threat to all countries.

Two proteins from the tuberculosis bacterium have shown promising results in investigations for a new vaccine in mice. Scientists from Universitas Gadjah Mada (UGM) in Yogyakarta, with colleagues from the Centenary Institute and the University of Sydney in Australia, have found that the injected proteins can prime the immune system to induce protection against TB in mice.

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Reinventing catalysts

Professor Thomas Maschmeyer is working to integrate new battery and solar cell technologies into the walls and roofs of new houses, and to transform the somewhat ‘black art’ of catalysis—the process that cracks crude oil into useful fuels, oils and chemicals at every refinery. He has already helped to create over 200 new jobs with four spin-out companies.

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Collaborating to combat killers

Indonesian and Australian researchers are working together to combat two big killers: pneumonia, and tuberculosis.

Around six million young Indonesians catch pneumonia each year, according to a 2008 study, and it’s the number one killer of children under five. Researchers now think there might be a link to how much time kids are spending out in the sunshine—more specifically, their level of vitamin D.

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The walls and roof are battery

Lithium batteries have transformed power storage—from smartphones to electric cars and submarines. But like every battery their chemical composition changes through every charge cycle.

Lithium ions sitting in layers of graphite move between electrodes and change the oxidation state of, magnesium oxide, for example. The chemical rearrangements cause the graphite and oxide layers to physically expand and contract by up to 15 per cent at every cycle, cracking and detaching from the electrodes.

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Indonesian and Australian scientists test new TB vaccine targets

Better vaccines are needed for the global fight against tuberculosis (TB). The Global Fund reports an estimated nine million new cases globally per year of TB, which is second only to AIDS as the world’s most deadly infectious disease.

Indonesia had more than 320,000 reported cases in 2014 according to the World Health Organization, while Australia’s reported cases were just over 1,000. But the rise of drug-resistant TB poses a threat to all countries.

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Reducing the impact of earthquakes

Working together, researchers in Japan and Australia are getting better at predicting the areas most at risk from earthquakes.

They are also working together on ways to determine, within seconds of a warning, the scale and likely impact of an earthquake.
Rapid detection and warning systems combined with smart engineering saved many lives in the Great Japanese Earthquake of 2011. But the earthquake and the resulting tsunami were much bigger than geological modelling suggested. The reasons for that might be found in deep history.

Mapping the hazard

Big earthquakes may be separated by centuries or millennia. But earthquake hazard maps are based on information gathered since 1900 when modern seismographs came into use. It’s difficult to model events happening over millennia when you have not got deep historical information. Continue reading Reducing the impact of earthquakes

Australian Academy of Science Early-career Awards

Julie Arblaster’s climate research is helping to explain the climate of the Australian region, particularly the ozone hole, El Niño, the monsoon, and Australian rainfall variability.

David Warton is driving data analysis in ecology, making it a more predictive science. His tools are influencing statistics across science and industry.

Christian Turney has pioneered new ways of combining climate models with records of past climate change spanning from hundreds to thousands of years.

Maria Seton has redefined the way we reconstruct the movement of continental plates and contributed to studies on the effect ocean basin changes have had on global long-term sea level and ocean chemistry. Continue reading Australian Academy of Science Early-career Awards

How Australia and India broke up—100 million years ago

Dr Joanne (Jo) Whittaker, Institute for Marine and Antarctic Studies, University of Tasmania, Hobart

Dr Joanne (Jo) Whittaker likes to solve jigsaw puzzles. Now this marine geoscientist is tackling the biggest puzzle on the planet—the formation of continents.
With SDP_0059 the help of Australia’s national marine research vessels, and now her L’Oréal Fellowship, Jo is reconstructing how the Indian, Australian and Antarctic tectonic plates separated over the past 200 million years, forming the Indian Ocean and the continents as we see them today. This information will help us model climate change better, find new gas resources, and understand the dynamics of the land in which we live.

The piece of this jigsaw she is now working on centres on two underwater plateaux, the Batavia and Gulden Draak Knolls, towering about 3000 metres above the Perth Abyssal Plain (PAP), which is around 1600 kilometres off the coast of Geraldton in Western Australia. In November 2011, Jo’s team mapped and sampled rocks from both knolls. Based on the evidence so far, Jo says, it looks like they split from the margins of the moving Indian Plate about 100 million years ago.
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