Keeping ahead of a child killer: stopping gastro from birth

UPDATE 22 February 2018:  

A vaccine has been developed against rotavirus, which is the common cause  of severe diarrhoea and a killer of approximately 215,000 children under five globally each year.

The oral vaccine was given in three single doses, the first within five days of birth. After three doses of RV3-BB administered from birth:

  • 94 per cent of infants were protected in their first year of life against severe rotavirus gastroenteritis
  • 75 per cent of infants were protected to 18 months of age.

The success of the RV3-BB vaccine is the culmination of more than four decades of work, which started with the Murdoch Children’s Research Institute’s Professor Ruth Bishop and the discovery of rotavirus in 1973.

The trial was funded by the National Health and Medical Research Council (NHMRC), Bill & Melinda Gates Foundation and PT BioFarma.

Read the full media release on the MCRI website.

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A new rotavirus vaccine should soon be available thanks to a collaboration between PT Bio Farma and researchers in Melbourne and Yogyakarta. The new ‘RV3’ vaccine is aimed at protecting babies from birth, improving protection and simplifying delivery.

The current vaccine, available in Australia and only on the private market in Indonesia, can only be administered from six weeks of age.

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Building port cities

Port cities can be lively, vibrant hives of activity—the hub of a nation’s economic health—if they’re planned well.

Indonesia’s busiest port, Tanjung Priok, has roughly two and a half times the container traffic as the Port of Melbourne. But it also has a reputation as one of the least efficient ports in Asia. Indonesian President Joko Widodo has recognised the need to transform the nation’s ports and plans to develop 24 new ports by 2019. One recently established, state-of-theart port is Teluk Lamong in Surabaya.

Continue reading Building port cities

Designing the coolest and most efficient tropical houses

Traditional buildings in Indonesia make use of ‘passive’ cooling techniques.

Being well ventilated, raised off the ground, and with shady verandas, their design allows them to stay cool in a tropical climate without air conditioning. The classic timber ‘Queenslander’ house also follows a similar design.

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An end to Indonesia’s hospital power blackouts? Sensing reductions in energy use

A team from Universitas Gadjah Mada (UGM) and the Australian National University (ANU) are planning to use thousands of sensors to monitor heat, noise, human activity and power usage in commercial buildings in Yogyakarta. This data will help them design a real-time monitoring system that saves energy and can be used in commercial buildings across Indonesia.

Energy demand in Indonesia has grown by 150 per cent over the last 30 years. Electricity supply is struggling to keep up—blackouts are common in hospitals, hotels, offices, shopping centres and university laboratories.

Continue reading An end to Indonesia’s hospital power blackouts? Sensing reductions in energy use

Can sunshine help prevent pneumonia?

A link between vitamin D deficiency and pneumonia is being investigated in two studies by Indonesian and Australian scientists in Indonesia.

They’re tracking the incidence and severity of respiratory tract infections in early childhood,including the common cold, asthma,pneumonia, and bronchiolitis, in hospitals and the community, in the hope of providing more information for treatment and management for respiratory diseases.

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The future of Indonesian mental health

Scientists are bringing together the knowledge from 300 mental health experts in a multi-disciplinary project to reimagine the future of mental healthcare in Indonesia.

Conducting interviews about policy, key challenges, case studies and patient groups, they’re looking to understand how new practices can fit into the historical, sociological and anthropological aspects of psychiatry in Indonesia.

Continue reading The future of Indonesian mental health

New targets for tuberculosis vaccine

Better vaccines are needed for the global fight against tuberculosis (TB) with nine million new cases annually. Indonesia had more than 320,000 reported cases in 2014, while Australia’s reported cases were just over 1,000. But the rise of drug-resistant TB poses a threat to all countries.

Two proteins from the tuberculosis bacterium have shown promising results in investigations for a new vaccine in mice. Scientists from Universitas Gadjah Mada (UGM) in Yogyakarta, with colleagues from the Centenary Institute and the University of Sydney in Australia, have found that the injected proteins can prime the immune system to induce protection against TB in mice.

Continue reading New targets for tuberculosis vaccine

Breeding mosquitoes to eliminate dengue.

In 2014, residents of Yogyakarta started growing and releasing mosquitoes. It’s counter-intuitive, but the mosquitoes carry Wolbachia bacteria, which reduces the risk of them spreading dengue fever.

Over a number of weeks, mosquitoes with Wolbachia breed with local mosquitoes and pass the bacteria on to their offspring until almost all mosquitoes in the area carry the disease-blocking microbes.

Continue reading Breeding mosquitoes to eliminate dengue.