Tag Archives: Bio Farma

Keeping ahead of a child killer: stopping gastro from birth

UPDATE 22 February 2018:  

A vaccine has been developed against rotavirus, which is the common cause  of severe diarrhoea and a killer of approximately 215,000 children under five globally each year.

The oral vaccine was given in three single doses, the first within five days of birth. After three doses of RV3-BB administered from birth:

  • 94 per cent of infants were protected in their first year of life against severe rotavirus gastroenteritis
  • 75 per cent of infants were protected to 18 months of age.

The success of the RV3-BB vaccine is the culmination of more than four decades of work, which started with the Murdoch Children’s Research Institute’s Professor Ruth Bishop and the discovery of rotavirus in 1973.

The trial was funded by the National Health and Medical Research Council (NHMRC), Bill & Melinda Gates Foundation and PT BioFarma.

Read the full media release on the MCRI website.

——

A new rotavirus vaccine should soon be available thanks to a collaboration between PT Bio Farma and researchers in Melbourne and Yogyakarta. The new ‘RV3’ vaccine is aimed at protecting babies from birth, improving protection and simplifying delivery.

The current vaccine, available in Australia and only on the private market in Indonesia, can only be administered from six weeks of age.

Continue reading Keeping ahead of a child killer: stopping gastro from birth

A five-in-one vaccine for all Indonesian children

Indonesia is rolling out a five-in-one vaccine that they plan to deliver in a single shot to every Indonesian child to protect them against diphtheria, tetanus, whooping cough, hepatitis B and Haemophilus influenzae type B (Hib).

The rollout is supported by the Australian Government through GAVI, the global vaccine alliance. The vaccine is manufactured by Bio Farma, who also hope to add rotavirus to the vaccines in the future.

Boosting vaccine performance

Vaccines work best when they include an adjuvant, something that boosts your immune system’s reaction to the vaccine.

University of Melbourne researchers have recreated a fragment of a bacteria protein that activates white blood cells.

In 2012, they signed a research agreement with Bio Farma to help them turn their idea into a novel vaccine platform that could enhance vaccines for hepatitis, diphtheria, tetanus, whooping cough, and other diseases.

A universal flu vaccine

A broad-spectrum flu vaccine is being developed to give better immunity to seasonal influenza strains and increased protection against future influenza pandemics.

The technology was created by researchers at the Australian National University and the University of Adelaide, who set up Gamma Vaccines to commercialise their ideas.

In 2013, Gamma Vaccines signed a three-way development agreement with Bio Farma and SOHO Industri Pharmasi to develop, manufacture, trial, and distribute the vaccine in Indonesia and other Association of Southeast Asian Nations (ASEAN) countries.