Building a better banana

The Bill and Melinda Gates Foundation are supporting the efforts of Queensland University of Technology scientists to design a better banana.

James Dale and a better banana palm for Africa. Credit: QUT
James Dale and a better banana palm for Africa. Credit: QUT

The researchers have already added provitamin A—a compound the body converts to Vitamin A—to the East African Highland banana. Now they are working to boost the iron content of the cooking banana that is a staple food of Uganda.

Led by Prof James Dale, director of University’s Centre for Tropical Crops and Biocommodities, the researchers are working with the Ugandan National Agricultural Research Organisation to modify the bananas genetically to raise their micronutrient levels, and then develop disease-resistant strains to distribute to East African farmers. The research is being funded by a $10-million grant from Bill and Melinda Gates Foundation’s Grand Challenges in Global Health Program.

James and his team developed efficient technology for raising nutrient levels in Cavendish bananas through to field trials in Queensland and then transferred it to Uganda. Ugandan scientists are now using these methods to modify East African Highland bananas genetically to increase their biosynthesis of provitamin A and their accumulation of iron.

Part of the project includes ensuring Ugandans will accept the new fruit, which has deep yellow flesh, thanks to the addition of the Vitamin A precursor, beta-carotene.

Saving koalas by vaccination

The first Australian trials have started of a vaccine to prevent koalas from contracting and spreading the deadly sexually transmitted disease, chlamydia.

Saving koalas by vaccination
Professor Peter Timms is trialling a Chlamydia vaccine for koalas. Credit: QUT

The trials—supervised by Prof Peter Timms and Prof Ken Beagley from Queensland University of Technology (QUT)’s Institute of Health and Biomedical Innovation—have been undertaken safely both in healthy koalas and koalas that already have chlamydial disease. All vaccinated koalas developed a good immune response to the anti-chlamydia vaccine, which shows great promise of making a significant impact on the disease in the near future.

Chlamydia is a major threat to the continued survival of koalas. Almost all populations in Australia are affected by the disease. It is a significant cause of infertility, urinary tract infections, and inflammation in the lining of the eye which often leads to blindness.

Koala numbers are declining across virtually its whole range. In the Koala Coast region of southeast Queensland in 2008 it was estimated that 2332 koalas had been lost in a three-year monitoring period. That represented a 51 per cent decrease.

By studying chlamydial disease in koalas, QUT researchers hope to understand the condition better in general. They believe their work may also hold the key to developing a successful vaccine for use against the human sexually transmitted disease Chlamydia trachomatis, a major cause of infertility in women.

Photo: Professor Peter Timms is trialling a Chlamydia vaccine for koalas.
Credit: QUT

Institute of Health and Biomedical Innovation, QUT, Peter Timms, Tel: +61 7 3138 6199, p.timms@qut.edu.au; www.ihbi.qut.edu.au/

Improved myopia treatment in sight

New glasses that slow the progression of short-sightedness or myopia are now available. The glasses which incorporate a novel lens design could potentially benefit some of the 3.6 million Australians with myopia and hundreds of millions of people worldwide.

New corrective lenses slow the progression of short-sightedness. Credit: iStockphoto
New corrective lenses slow the progression of short-sightedness. Credit: iStockphoto

Until now, correcting myopia has relied on measuring the clarity of vision at the very centre of the retina. Corrective lenses were designed to provide the wearer with clear central vision but did nothing for peripheral vision. Studies have now shown that short-sightedness progressively worsens in spite of correction using these traditional lenses.

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Ocean acidification threatens marine ecosystems

Ocean acidification, caused by increasing amounts of atmospheric carbon dioxide dissolving in the ocean, poses a serious threat to marine ecosystems.

Increasing acidity affects the ability of some planktonic organisms to form shells, and is expected to change the species composition of plankton, with flow-on effects to higher levels of the food web.

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The kangaroo genome – marsupials filling the gap

Analysing the genomes of Australia’s iconic marsupials will provide insight into how they turn off and on the development of the early embryo; give birth to very underdeveloped young, and why marsupial milk changes radically over the months of lactation.

This knowledge could lead scientists to new treatments for premature births, better milk production in cows, as well as novel antibiotics. Marsupials fill an evolutionary gap between the distantly related birds/reptiles and the more closely related placental mammals (such as humans and cows).

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Researcher to fight insects with spider venom

An Australian researcher is working on environmentally friendly insect control methods based on spider venom compounds.

Professor Glenn King recently joined The University of Queensland’s Institute for Molecular Bioscience, where he will further develop his pioneering approach to insecticide discovery.

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Animals contribute to greenhouse gases

Smoke-belching coal-fired power stations and factories and fossil fuel-guzzling motor vehicles may be seen as the big villains of the global climate change debate, but they aren’t the only ones contributing to the greenhouse effect.

Australia’s hundreds of millions of cattle, sheep, pigs and other agricultural animals – not to mention our native fauna – also release significant amounts of methane and other gases into the atmosphere.

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