Tag Archives: crystallography

Clues to switching off your blood clots

Our blood has a built-in system for breaking up heart attack-inducing clots—and we’re a step closer to drugs that could switch that system on at will.

The molecular structure of plasminogen Credit: Prof James Whisstock/Australian Synchrotron
The molecular structure of plasminogen. Credit: Prof James Whisstock/Australian Synchrotron

Australian researchers have won the decades-long race to define the structure of plasminogen—a protein whose active form quickly dissolves blood clots.

The current crop of clot-busting drugs have many side effects, including bleeding and thinning of the blood, so harnessing the body’s own mechanism for clearing clots could offer a better way. Continue reading Clues to switching off your blood clots

Shattering the crystal lattice

Watson and Crick’s discovery of the structure of DNA is arguably the greatest of the 20th century. The significance lies in its profound influence on our understanding of the nature of life and in its striking demonstration of the power of two disciplines – physics and biology – collaborating to solve a major problem.

Continue reading Shattering the crystal lattice