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2016 Prime Minister’s Prizes for Science
Tag Archives: peptides
Frog peptides versus superbugs
Neutrons and native frogs are an unlikely but dynamic duo in the battle against antibiotic-resistant bacteria, commonly known as superbugs, recent research has shown.
The skin secretions of the Australian green-eyed and growling grass frogs contain peptides (small proteins) that help frogs fight infection. Researchers hope these peptides will offer a new line of defence against a range of human bacterial pathogens, including methicillin-resistant Staphylococcus aureus (MRSA).
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Pain relief from the sea
For the one in five Australians of working age suffering from serious chronic pain, the options for relief are strictly limited. There’s morphine and . . . well, there’s morphine. But now one of the most powerful toxins in the natural world—the venom of marine cone snails—offers hope of a future free of pain and addiction, say researchers at RMIT University.
“The big problems with morphine are addictiveness and the fact that people develop a tolerance to it,” says Professor David Adams, director of the RMIT Health Innovations Research Institute. “With the painkillers derived from cone snail venom, we don’t have those problems. People don’t develop tolerance, and they don’t get hooked.
Milk could soothe the savage gum
Melbourne dental health researchers have discovered a painless, low-cost treatment which may prevent gum disease.
And the key ingredients—protein fragments known as peptides—come from cows’ milk.
The link between the peptides and gum disease was forged at the Melbourne Dental School node of the Oral Health Cooperative Research Centre by Dr Elena Toh. “This could provide a cheap and simple way to help prevent gum disease,” she says. “And because the peptides are derived from milk, there should be no toxicity issues.”
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Venom from the sea cures human pain
The University of Melbourne’s Departments of Biochemistry and Molecular Biology, and Pharmacology have over recent years identified cone shell venom as a potential treatment for chronic pain in humans.
Researchers continue to develop the research into a commercialised product. One of the venom peptides identified is currently in phase two of clinical trials.