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2013, L’Oréal For Women in Science

Tracking the spread of deadly diseases

Dr Kathryn (Kat) Holt, Bio21 Institute, The University of Melbourne

Kathryn-Holt-700x500-2 Kat Holt is using genetics, maths and supercomputers to study the whole genome of deadly bacteria and work out how they spread. Studying a typhoid epidemic in Kathmandu, she found that it didn’t spread in the way we thought epidemics did. Her research, published in Nature Genetics, will change how we go about responding to epidemics.

With the support of her L’Oréal For Women in Science Fellowship, Kat will be using the same techniques to understand how antibiotic-resistant bacteria spread in Melbourne hospitals. Are people catching these superbugs in hospital, or are they bringing the bugs into hospital with them? Can we give the intensive care clinicians early warning of a drug-resistant bacteria in their patients?

Kathryn (Kat) has been a pioneer ever since she became the first student at the University of Western Australia to undertake an honours year in the then-fledgling area of bioinformatics.

Kat ventured across the Nullarbor to the other side of Australia—to the Walter and Eliza Hall Institute of Medical Research in Melbourne—where she sought advice from bioinformatics guru Prof Terry Speed. As a result, she ended up as a doctoral student at the world renowned Sanger Institute at the University of Cambridge, one of the homes of the human genome project.
Continue reading Tracking the spread of deadly diseases →

2013, L’Oréal For Women in Science

How Australia and India broke up—100 million years ago

Dr Joanne (Jo) Whittaker, Institute for Marine and Antarctic Studies, University of Tasmania, Hobart

Dr Joanne (Jo) Whittaker likes to solve jigsaw puzzles. Now this marine geoscientist is tackling the biggest puzzle on the planet—the formation of continents.
With SDP_0059 the help of Australia’s national marine research vessels, and now her L’Oréal Fellowship, Jo is reconstructing how the Indian, Australian and Antarctic tectonic plates separated over the past 200 million years, forming the Indian Ocean and the continents as we see them today. This information will help us model climate change better, find new gas resources, and understand the dynamics of the land in which we live.

The piece of this jigsaw she is now working on centres on two underwater plateaux, the Batavia and Gulden Draak Knolls, towering about 3000 metres above the Perth Abyssal Plain (PAP), which is around 1600 kilometres off the coast of Geraldton in Western Australia. In November 2011, Jo’s team mapped and sampled rocks from both knolls. Based on the evidence so far, Jo says, it looks like they split from the margins of the moving Indian Plate about 100 million years ago.
Continue reading How Australia and India broke up—100 million years ago →

2013, L’Oréal For Women in Science

When killing saves lives: our immune system at work

Dr Misty Jenkins, Peter MacCallum Cancer Centre, Melbourne

Misty-Jenkins-700x500 Dr Misty Jenkins spends a lot of her time watching killers at work: the white blood cells of the body that eliminate infected and cancerous cells. She can already tell you a great deal about how they develop into assassins and arm themselves. Now with the support of her L’Oréal For Women in Science Fellowship Misty is exploring how they become efficient serial killers—killing one cancer cell in minutes and moving on to hunt down others. Her work will give us a greater understanding of our immune system and open the way to better manage T cells to defeat disease.

Misty’s career so far has been quite a journey for a girl from Ballarat. Along the way she been mentored by Nobel Prize-winning immunologist Prof Peter Doherty and become the first Indigenous Australian to attend either Oxford or Cambridge. Now working with Prof Joe Trapani as a National Health and Medical Research Council  (NHMRC) postdoctoral fellow in the Cancer Cell Death laboratory at the Peter MacCallum Cancer Centre in Melbourne, Misty has been awarded a $25,000 L’Oréal Australia and New Zealand For Women in Science Fellowship. She will use the money to further her study of what triggers T cells to detach themselves from their targets and seek additional prey.
Continue reading When killing saves lives: our immune system at work →

2012, L’Oréal For Women in Science

Giving patients more control of their lives

Dr Suetonia Palmer

University of Otago, Christchurch, New Zealand

Dr Suetonia Palmer is challenging the status quo for kidney disease treatment and helping millions of people with chronic kidney disease take back control of their lives.

Click image for hi-res. Photo: Dr Suetonia Palmer, University of Otago (credit: L’Oréal Australia/sdpmedia.com.au)
Click image for hi-res. Photo: Dr Suetonia Palmer, University of Otago (credit: L’Oréal Australia/sdpmedia.com.au)

Working from temporary facilities as Christchurch rebuilds, she is guiding doctors and policy makers across the world as they attempt to make the best decisions for their patients.

Continue reading Giving patients more control of their lives →

2012, L’Oréal For Women in Science

More efficient solar cells with quantum dots

Dr Baohua Jia

Swinburne University of Technology, Melbourne, Australia

The global race to develop high efficiency, low cost solar energy is fierce. And Baohua Jia and her colleagues are front runners.

Click image for hi-res. Photo: Dr Baohua Jia, Swinburne University of Technology (credit: L’Oréal Australia/sdpmedia.com.au)
Click image for hi-res. Photo: Dr Baohua Jia, Swinburne University of Technology (credit: L’Oréal Australia/sdpmedia.com.au)

Conventional solar cells are efficient, but thick and expensive. Baohua and her colleagues imagine a future when solar cells are so thin and cheap that city skyscrapers will be powered by a coating on their glass. But at present such thin-film solar cells are not efficient enough for general use.

Using her knowledge of nanotechnology and optics, Baohua and her colleagues have already created thin-film solar cells that are more than 20 per cent more efficient than those of her competitors. They have already lodged two patents.

But Baohua thinks she can do better. And that will be the focus of the work assisted by her $25,000 L’Oréal Australia & New Zealand For Women in Science Fellowship.

Continue reading More efficient solar cells with quantum dots →

2012, L’Oréal For Women in Science

New treatments for blood cancers

Dr Kylie Mason

Walter and Eliza Hall Institute of Medical Research/Royal Melbourne Hospital, Melbourne, Australia

Click image for hi-res. Photo: Dr Kylie Mason, Walter and Eliza Hall Institute of Medical Research/Royal Melbourne Hospital (credit: L’Oréal Australia/sdpmedia.com.au)
Click image for hi-res. Photo: Dr Kylie Mason, Walter and Eliza Hall Institute of Medical Research/Royal Melbourne Hospital (credit: L’Oréal Australia/sdpmedia.com.au)

Dr Kylie Mason has set herself the goal of developing new ways of treating diseases that are considered incurable.

Continue reading New treatments for blood cancers →

2012

Health check for live cells

Unhealthy cells are less “squishy” than their healthy counterparts. That difference is used by a small device developed by engineers at Monash University to test living blood cells for diseases, such as malaria and diabetes. The device can then sort the cells for future culturing and experimentation without harming them.

A simulation of a red blood cell being trapped and strained for measurement in the Monash device. Credit: Yann Henon, Andreas Fouras & Greg Sheard
A simulation of a red blood cell being trapped and strained for measurement in the Monash device. Credit: Yann Henon, Andreas Fouras & Greg Sheard

The patented “lab-on-a-chip” and accompanying control system has attracted considerable interest from pharmaceutical companies, according to co-inventor Dr Greg Sheard of the Department of Mechanical and Aerospace Engineering. Continue reading Health check for live cells →

2012

Birds, bees, robots and flying

He isn’t a pilot, but few people would know more about ways of navigating while flying than Prof Mandyam Srinivasan (Srini) of the Queensland Brain Institute. And he’s steadily finding out more.

Srinivasan works on bee navigation: here he is in the All-Weather Bee Flight Facility at the Queensland Brain Institute (QBI) Credit: Dee McGrath/QBI
Srinivasan works on bee navigation: here he is in the All-Weather Bee Flight Facility at the Queensland Brain Institute (QBI). Credit: Dee McGrath/QBI

Initially known for his work in bees, since receiving the Prime Minister’s Prize for Science in 2006, Srini has shown that birds and insects use a similar system of visual guidance to prevent themselves from crashing into trees when flying through dense forest.

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Stories of Astronomy 2012

Japanese spacecraft calls Australia home

AN ARTIST’S IMPRESSION OF THE HAYABUSA SPACECRAFT APPROACHING THE ASTEROID ITOKAWA. CREDIT: A. IKESHITA/MEF/ISAS.
AN ARTIST’S IMPRESSION OF THE HAYABUSA SPACECRAFT APPROACHING THE ASTEROID ITOKAWA. CREDIT: A. IKESHITA/MEF/ISAS.

On 13 June 2010, a Japanese spacecraft bearing pieces of another world parachuted down to Australian soil after a seven-year-long journey through deep space.

During its journey, the spacecraft, called Hayabusa, encountered the 530-metre-long asteroid called Itokawa in November 2005, and briefly landed on it. The Japanese Aerospace Exploration Agency (JAXA) designed Hayabusa to collect samples of the asteroid’s surface. Hayabusa then landed at the Department of Defence’s remote Woomera Prohibited Area in the South Australian desert. Fifty years ago, Woomera was one of the most active rocket launch sites in the world. It is still the largest land-based test range on the planet. Continue reading Japanese spacecraft calls Australia home →

Stories of Astronomy 2012

The destruction of a star

THE ZADKO TELESCOPE MAKING OBSERVATIONS NEAR GINGIN, 70 KILOMETRES NORTH OF PERTH. CREDIT: JOHN GOLDSMITH/CELESTIAL VISIONS.
THE ZADKO TELESCOPE MAKING OBSERVATIONS NEAR GINGIN, 70 KILOMETRES NORTH OF PERTH. CREDIT: JOHN GOLDSMITH/CELESTIAL VISIONS.

You have to be well prepared, quick and lucky to take a picture of an explosion, especially if that explosion occurred 11 billion years ago in a remote part of the Universe. Having the right equipment, plus friends in high places, certainly helps. And that’s exactly what the Zadko Telescope—managed by the University of Western Australia at the Gingin Observatory about 70 kilometres north of Perth—does have.

In December 2008, just after it was installed, the telescope was first on the scene to record for future analysis the afterglow of a momentous event—a huge explosion as a star collapsed into a black hole releasing a massive gamma-ray burst. It’s the kind of happening the one-metre Zadko Telescope, currently the largest optical telescope in Western Australia, was built to observe. And it performed flawlessly, outpacing the world’s most powerful telescopes at the European Southern Observatory in Chile.

Continue reading The destruction of a star →