Saving koalas by vaccination

The first Australian trials have started of a vaccine to prevent koalas from contracting and spreading the deadly sexually transmitted disease, chlamydia.

Saving koalas by vaccination
Professor Peter Timms is trialling a Chlamydia vaccine for koalas. Credit: QUT

The trials—supervised by Prof Peter Timms and Prof Ken Beagley from Queensland University of Technology (QUT)’s Institute of Health and Biomedical Innovation—have been undertaken safely both in healthy koalas and koalas that already have chlamydial disease. All vaccinated koalas developed a good immune response to the anti-chlamydia vaccine, which shows great promise of making a significant impact on the disease in the near future.

Chlamydia is a major threat to the continued survival of koalas. Almost all populations in Australia are affected by the disease. It is a significant cause of infertility, urinary tract infections, and inflammation in the lining of the eye which often leads to blindness.

Koala numbers are declining across virtually its whole range. In the Koala Coast region of southeast Queensland in 2008 it was estimated that 2332 koalas had been lost in a three-year monitoring period. That represented a 51 per cent decrease.

By studying chlamydial disease in koalas, QUT researchers hope to understand the condition better in general. They believe their work may also hold the key to developing a successful vaccine for use against the human sexually transmitted disease Chlamydia trachomatis, a major cause of infertility in women.

Photo: Professor Peter Timms is trialling a Chlamydia vaccine for koalas.
Credit: QUT

Institute of Health and Biomedical Innovation, QUT, Peter Timms, Tel: +61 7 3138 6199, p.timms@qut.edu.au; www.ihbi.qut.edu.au/

Is that you in the video?

Is that you in the video?
Clinton Fookes is technical director of QUT’s Airports of the Future. Credit: Queensland University of Technology (QUT).

A Queensland University of Technology (QUT) engineer is developing techniques to automatically identify people in surveillance videos and recognise their movement and behaviour.

The explosion of video surveillance to make public places safer, says Dr Clinton Fookes of the University’s School of Engineering Systems, has created a new challenge for researchers—to make sense of what cameras and computers see. So he is investigating ways to extract and interpret important information from these visual sources.

The data generated by the proliferation of surveillance cameras, as well as the countless images and videos online, he says, are impossible to intelligently use without sophisticated computer vision technology that can automatically extract information from these sources, collate and report on it in real time.

As Clinton’s work is ideally suited to improving security in public places such as airports, one of his roles is technical director of QUT’s Airports of the Future—a major research project aimed at improving the experience of passengers passing through Australia’s airports.

His research in this field could lead to new discoveries in a range of areas including human-computer interaction, security, medical imaging and robotics.

Photo: Clinton Fookes is technical director of QUT’s Airports of the Future.
Credit: QUT

School of Engineering Systems, QUT, Clinton Fookes, Tel: + 61 7 3138 2458, c.fookes@qut.edu.au, staff.qut.edu.au/staff/fookes/

Improved myopia treatment in sight

New glasses that slow the progression of short-sightedness or myopia are now available. The glasses which incorporate a novel lens design could potentially benefit some of the 3.6 million Australians with myopia and hundreds of millions of people worldwide.

New corrective lenses slow the progression of short-sightedness. Credit: iStockphoto
New corrective lenses slow the progression of short-sightedness. Credit: iStockphoto

Until now, correcting myopia has relied on measuring the clarity of vision at the very centre of the retina. Corrective lenses were designed to provide the wearer with clear central vision but did nothing for peripheral vision. Studies have now shown that short-sightedness progressively worsens in spite of correction using these traditional lenses.

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Mopping up gases

Deanna D’Alessandro

University of Sydney

A sponge that filters hot air and captures carbon dioxide

Deanna D’Alessandro, The University of Sydney (credit: L’Oréal Australia/sdpmedia.com.au)
Deanna D’Alessandro, The University of Sydney (credit: L’Oréal Australia/sdpmedia.com.au)

We need better ways of capturing carbon dioxide emissions from power stations and industry. And we won’t be using hydrogen cars until we’ve developed practical ways of carrying enough hydrogen gas in the fuel tank. Deanna D’Alessandro’s understanding of basic chemistry has led her to create new, incredibly absorbent chemicals that could do both these jobs and much more.

It’s all to do with surface area. Working in California and in Sydney she has constructed crystals that are full of minute holes. One teaspoon of the most effective of her chemicals has the surface area of a rugby field. What’s more, the size and shape of the pores can be customised using light. So she believes she can create molecular sponges that will mop up carbon dioxide, hydrogen, or in theory almost any gas – and then release it on cue. Continue reading Mopping up gases

Fighting back against malaria

Rowena Martin

The Australian National University, Canberra/The University of Melbourne

Rowena Martin, The Australian National University, Canberra/The University of Melbourne (credit: L’Oréal Australia/sdpmedia.com.au)
Rowena Martin, The Australian National University, Canberra/The University of Melbourne (credit: L’Oréal Australia/sdpmedia.com.au)

In the 1950s it seemed as if medical science was winning the fight against malaria with the help of the ‘wonder drug’ chloroquine. Over the past half century the drug has saved hundreds of millions of lives.

But now the parasite that causes malaria has fought back. Chloroquine-resistant malaria has become common in developing countries. Rowena Martin is working to understand what happened, and to develop new ways of treating malaria. Continue reading Fighting back against malaria

How does breast cancer start?

Marie-Liesse Asselin-Labat

Walter and Eliza Hall Institute of Medical Research

Most women in Australia who have breast cancer recover.  But many then relapse years later.

Rowena Martin, The Australian National University, Canberra/The University of Melbourne (credit: L’Oréal Australia/sdpmedia.com.au)
Rowena Martin, The Australian National University, Canberra/The University of Melbourne (credit: L’Oréal Australia/sdpmedia.com.au)

Marie-Liesse Asselin-Labat wants to know why.  If she can solve this mystery, her work will open up opportunities for new drugs and treatments. Her achievements to date suggest that she is well placed to succeed.

In 2006 she was part of the Walter and Eliza Hall Institute of Medical Research team that received global attention for its discovery of breast stem cells – a significant step in understanding how breast cancer starts. Marie-Liesse built on this finding with a series of papers exploring how these cells develop and are influenced by oestrogen and other steroids. Continue reading How does breast cancer start?

No moving parts – a new kind of radio telescope

Murchison Widefield Array
The Murchison Widefield Array is one of the first telescopes with no moving parts. Credit: David Herne, ICRAR

Far outback in Western Australia, at the Murchison Radio Astronomy Observatory located on Boolardy Station, 315 km north-east of Geraldton, 32 tiles each carrying 16 dipole antennas have begun to collect scientific data on the Sun. At the same time they are providing engineering information to be used to extend the facility to a much bigger array of 512 tiles – the Murchison Widefield Array (MWA).

Continue reading No moving parts – a new kind of radio telescope

Ocean acidification threatens marine ecosystems

Ocean acidification, caused by increasing amounts of atmospheric carbon dioxide dissolving in the ocean, poses a serious threat to marine ecosystems.

Increasing acidity affects the ability of some planktonic organisms to form shells, and is expected to change the species composition of plankton, with flow-on effects to higher levels of the food web.

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The kangaroo genome – marsupials filling the gap

Analysing the genomes of Australia’s iconic marsupials will provide insight into how they turn off and on the development of the early embryo; give birth to very underdeveloped young, and why marsupial milk changes radically over the months of lactation.

This knowledge could lead scientists to new treatments for premature births, better milk production in cows, as well as novel antibiotics. Marsupials fill an evolutionary gap between the distantly related birds/reptiles and the more closely related placental mammals (such as humans and cows).

Continue reading The kangaroo genome – marsupials filling the gap

Australia’s new reactor opens

The OPAL reactor and new neutron beam facility, managed by the Australian Nuclear Science and Technology Organisation (ANSTO) in Sydney’s south, officially opens on Wednesday 18 April 2007.

Costing $400 million to build, the reactor was described by ANSTO’s Executive Director, Dr. Ian Smith as “the jewel in the crown” of Australian nuclear research.

Continue reading Australia’s new reactor opens

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