Changing lives: Australia–Japan science links

To read about Japan-Australia innovation collaborations—including searching for new malaria drugs, giant robot trucks carrying ore, and chewing gum that reverses tooth decay—click here.

Japanese science changing Australia

The impact of Japanese technological prowess on Australian society is obvious for all to see. How we listened to music was transformed by audio recording technologies: from the Walkman to the CD. Home entertainment was changed by video tapes, DVDs, and game consoles. We rely on Japanese innovation in transport—reliable car engineering, the lean manufacturing techniques that made them affordable and, more recently, hybrid cars.

Nobel Laureate Shinya Yamanaka changed stem cell science. Credit: Gladstone Institutes/Chris Goodfellow
Nobel Laureate Shinya Yamanaka changed stem cell science. Credit: Gladstone Institutes/Chris Goodfellow

Fundamental science discoveries are bringing a new era of transformation. Japanese researchers were honoured last year with the Nobel Prize for their invention of the blue LED. They succeeded where for 30 years everyone else had failed. Incandescent light bulbs lit the 20th century; the 21st century will be lit by LED lamps—lasting a lifetime and using a fraction of the energy.

In 2006 Shinya Yamanaka discovered how intact mature cells in mice could be reprogrammed to become immature stem cells. By introducing only a few genes, he could reprogram mature cells to become pluripotent stem cells, that is, immature cells that are able to develop into all types of cells in the body. His work is transforming stem cell medicine and many Australian researchers are now using induced pluripotent stem cells to develop stem cell medicines.

Continue reading Changing lives: Australia–Japan science links

Changing lives: Australia–Japan science links

Japanese science changing Australia

The impact of Japanese technological prowess on Australian society is obvious for all to see. How we listened to music was transformed by audio recording technologies: from the Walkman to the CD.

Nobel Laureate Shinya Yamanaka changed stem cell science. Credit: Gladstone Institutes/Chris Goodfellow
Nobel Laureate Shinya Yamanaka changed stem cell science. Credit: Gladstone Institutes/Chris Goodfellow

Home entertainment was changed by video tapes, DVDs, and game consoles. We rely on Japanese innovation in transport—reliable car engineering, the lean manufacturing techniques that made them affordable and, more recently, hybrid cars.

Fundamental science discoveries are now bringing a new era of transformation. Japanese researchers were honoured last year with the Nobel Prize for their invention of the blue LED. They succeeded where for 30 years everyone else had failed. Incandescent light bulbs lit the 20th century; the 21st century will be lit by LED lamps— lasting a lifetime and using a fraction of the energy.

In 2006 Shinya Yamanaka discovered how intact mature cells in mice could be reprogrammed to become immature stem cells. By introducing only a few genes, he could reprogram mature cells to become pluripotent stem cells, that is, immature cells that are able to develop into all types of cells in the body. His work is transforming stem cell medicine and many Australian researchers are now using his induced pluripotent stem cells to develop stem cell medicine.

Australian science changing Japan

It’s not a one way trade. Japanese lives are being improved by Australian inventions such as the bionic ear, gum that repairs tooth decay, sleep disorder treatments, lithium to treat bipolar disorder, aircraft black boxes, and anti-flu drugs, which are all in daily use in Japan.

And when you connect to a fast and reliable wi-fi network you can thank Australian astronomers who were searching for black holes and created tools for cleaning up radio waves.

Collaborating for the future

Today there are hundreds of thriving Australia–Japan research collaborations, many of which will have a profound impact on our lives in the years ahead.

Over the past five years, Japan has consistently placed within the 10 countries that have the highest number of collaborations with Australian researchers on Australian Research Council–funded projects. The ARC reports that the most popular disciplines for collaboration with Japan are: material engineering; biochemistry and cell biology; atomic, molecular, nuclear, particle and plasma physics; astronomical and space sciences and plant biology.

Other collaborations

Seeing every cell in a whole adult brain
Scientists from RIKEN, the University of Tokyo, JAST, and the Queensland University of Technology have developed CUBIC—a technique for rapidly imaging the brain. They believe it will be scalable to whole bodies.

Biomedical applications for ‘magic crystals’
CSIRO and Osaka Prefecture University are developing biomedical applications for the massively absorbent metal–organic framework crystals developed by CSIRO.

How our phones track us
Billions of us now have phones that tell us and others where we are and what’s around us. A team from RMIT, Intel, Fudan University and Keio University is exploring the cross-cultural and intergenerational study of this phenomenon, and the implications for privacy, in three key sites: Tokyo, Shanghai and Melbourne.

For more information: Science in Public, www.scienceinpublic.com.au/stories/japan

Pain relief from the sea

For the one in five Australians of working age suffering from serious chronic pain, the options for relief are strictly limited. There’s morphine and . . . well, there’s morphine. But now one of the most powerful toxins in the natural world—the venom of marine cone snails—offers hope of a future free of pain and addiction, say researchers at RMIT University.

PHOTO: CONE SNAILS MAY OFFER PAIN RELIEF. CREDIT: ISLAND EFFECTS
PHOTO: CONE SNAILS MAY OFFER PAIN RELIEF. CREDIT: ISLAND EFFECTS

“The big problems with morphine are addictiveness and the fact that people develop a tolerance to it,” says Professor David Adams, director of the RMIT Health Innovations Research Institute. “With the painkillers derived from cone snail venom, we don’t have those problems. People don’t develop tolerance, and they don’t get hooked.

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Faster flash flood warnings

Flash flooding, brought on by sudden torrential rain, killed dozens of people in Australia in 2011. Because of their very nature, it has been difficult to provide effective warnings. And that is a significant gap in Australia’s natural disaster management, according to the submission of RMIT University’s Centre for Risk and Community Safety to the 2011 Queensland Floods Commission of Inquiry.

Technology could mean more effective warnings against flash flooding, like the kind that hit Toowoomba, Queensland in January 2011. Credit: KingBob.net
Technology could mean more effective warnings against flash flooding, like the kind that hit Toowoomba, Queensland in January 2011. Credit: KingBob.net

We now have the technology to deliver such warnings, says director of the Centre, Prof John Handmer. “But using it would raise issues about how quickly both the authorities and people at risk are prepared to make critical decisions when they receive the information.”

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Curing cancer with radiation – safely

Prostate and other soft-tissue cancers are often treated with radioactive sources implanted or inserted into the body. But monitoring the dose is problematic.

Curing cancer with radiation – safely
Computer simulation of brachytherapy prostate treatment showing radioactive source trajectories through the pelvic region. Credit: Rick Franich
Medical physicists at Melbourne’s RMIT University are developing a technique to monitor the radiation dose more accurately.

In high dose rate brachytherapy, tumours are targeted by radioactive sources temporarily inserted into the body.

“Until now, it has not been possible to check at the time of delivery whether the doses received by the tumour and by surrounding healthy tissue matched the planned levels,” says Dr Rick Franich, Medical Radiation Physics group leader at the University’s Health Innovations Research Institute.
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A step towards an everlasting battery

Imagine a future where recharging your tablet could be as easy as typing a tweet—where portable electronic devices power themselves without ever plugging into the grid.

Pushing towards an everlasting battery
Electricity is generated as a force is applied to a piezoelectric film. Credit: Dr Daniel J. White
Researchers at RMIT University, Melbourne have assessed the capacity of piezoelectric films—thin layers that turn mechanical pressure into electricity—to do this.

The study is the first to evaluate how piezoelectric thin films, a thousandth of a millimetre thick, perform at the molecular level, precisely measuring the level of electrical voltage and current—and therefore, power—that could be generated.
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Understanding and responding to changing climate

ANU’s Chris Fulton measuring reef fish at Lizard Island. Credit: Neal Cantin
ANU’s Chris Fulton measuring reef fish at Lizard Island. Credit: Neal Cantin

From the poles to the tropics, researchers from Australia and the US are working together to watch and understand our changing natural world. America’s constellation of earth observation satellites plays a critical role in monitoring Australia’s changing climate and land use. During bushfire, flood and cyclone emergencies the information they provide is critical to Australia’s emergency response. The air sampled at remote Cape Grim on Tasmania’s northwest coast and Australia’s ice core research are two examples of Australia’s contribution to NASA and the US National Oceanic and Atmospheric Administration (NOAA) efforts to understand and predict the planet’s changing climate. Australia and the US both encompass a huge range of terrestrial and marine ecosystems. Australia’s experiences in dealing with fire, drought and natural disasters are helping to give US researchers a different perspective on some of the challenges of America’s changing climate and environment.

Remote sensing in natural disasters

Emergency response managers are able to track the course of natural disasters such as fires, floods, earthquakes and storms and plan with increased accuracy thanks to software developed by Associate Professor Linlin Ge and his team at the University of New South Wales in Sydney. The software allows data from interferometric synthesis aperture radar (INSAR) satellites to be pulled together rapidly and automatically to generate high-resolution maps. The maps reveal ground movements, and predict likely damage to vital infrastructure such as buildings, roads, railways and bridges.

The team’s work has led to the establishment of an international network of national remote sensing agencies that collaborate in times of emergency management. The network began spontaneously in 2008 when Associate Professor Ge and his team, confronted by the enormity of the Sichuan earthquake in China, helped local rescue workers by providing satellite images constructed from Japanese data.

Cape Grim’s clean air—monitoring global climate change

Australia provides baseline climate data to the rest of the world through its monitoring station at Cape Grim at the extreme northwest tip of Tasmania. As well as monitoring carbon dioxide, methane and a range of atmospheric trace gases, scientists at Cape Grim measure concentrations of natural and pollutant particles. Because of Cape Grim’s remoteness from population centers (Argentina is the only landmass west of the Cape), the collected data represents as close as scientists can measure to a global average. The monitoring station is managed jointly by Australia’s Bureau of Meteorology and CSIRO.

Keeping a weather eye out

Antarctic research and resupply Ship Aurora Australis. Credit: Natalia Galin
Antarctic research and resupply Ship Aurora Australis. Credit: Natalia Galin

In addition, CSIRO has made a long-term contribution to improved climate prediction through monitoring the Southern Ocean since 1994. The world’s largest current, the Antarctic Circumpolar Current, flows around the Southern Ocean connecting the three major ocean basins—Pacific, Indian and Atlantic—redistributing heat, affecting temperature and rainfall, and making a huge impact on the world’s climate.

Through agreements with NOAA, NASA, and the Scripps Institution of Oceanography in San Diego, a ground station in Hobart in the southern island state of Tasmania, operated by the Australian Centre for Remote Sensing, has been downloading climate-relevant data from passing US polar orbit satellites.

One thousand new species found—understanding coral reefs

In the tropics, researchers at the Australian Institute of Marine Science (AIMS) are working with counterparts in the US to discover and document life on coral reefs and monitor the impact of climate change. AIMS, NOAA and the Smithsonian Institution lead the three nodes of CReefs, the coral reef component of the Census of Marine Life. CReefs aims to discover and explain the diversity, distribution, and abundance of life in coral reef ecosystems, and improve access to and unify this information. Already, more than 1,000 previously undocumented species have been discovered on Australia’s Great Barrier Reef, along the east coast, and Ningaloo Reef, off the west coast, as part of the project.

Fixing the plumbing—water conservation

Along with susceptibility to forest fires, large areas of Australia and the US also are prone to drought and water shortages and the two countries have long collaborated on water research. The recent development of a Memorandum of Understanding on Environmental Water Cooperation between the two countries tackles an interesting consequence of water conservation. As the water efficiency of plumbing fixtures increases, there has been a significant reduction in the flows moving through the sewer system, increasing the concentration of waste and creating challenges for existing processing facilities. The memorandum covers joint research to be conducted in this area.

Elvis to the rescue

Experimental Bushfire Set In Mccorkhill, Western Australia. Credit: CSIRO.
Experimental Bushfire Set In Mccorkhill, Western Australia. Credit: CSIRO.

Each year, the ‘Elvis’ air-crane and other giant firefighting helicopters migrate south from America to Australia, where they have saved many Australian lives and properties. American fire fighters and fire investigators have also been helping on the ground, especially following Victoria’s Black Saturday bushfires in 2009. And the cooperation works both ways, with Australia contributing both firefighting expertise and research support in response to recent Californian wildfires. A meeting organized by Australia’s Bushfire Cooperative Research Centre in June 2010 has helped to broaden and formalize this collaboration, as researchers and fire managers from the US, New Zealand and Australia came together to share their knowledge and plan future collaborative work.

People

Fishy business

Dr Beth Fulton, based at CSIRO Marine and Atmospheric Research in Hobart and a former winner of the Prime Minister’s Life Scientist of the year award, is a world leader in modeling marine ecosystems. Dr Fulton works regularly with researchers from NOAA and US universities. Together they have developed management models for marine life along much of the west and east coasts of continental US, and now are studying the Gulf of Mexico and Hawaii.

Snow complications

The US and Australia maintain significant collaborative research programs in Antarctica, drilling ice cores that provide a detailed historical record of climate, and measuring the extent and thickness of the sea-ice, which has a major impact on climate. Fulbright scholar and University of Tasmania PhD student Ms Natalia Galin has been collaborating with researchers at the University of Kansas to measure snow thickness from a helicopter. An error in snow measurements above the water can be magnified by eight or nine times in estimating ice thickness below the water. However, the team’s specialized radar equipment provides accurate readings of snow thickness on sea ice—information that will be used to calibrate satellite remote sensing data.

The long-term view

An Australian paleontologist, who uncovered the earliest fossil of live birth in fishes, a key to our understanding of reproduction in animals with backbones, is now Vice-President Research and Collections at the Natural History Museum of Los Angeles County. Dr John Long was formerly Head of Sciences at Museum Victoria.

This is an part of a series of eight factsheets exploring US-Australian collaboration and outlining some of the ways that Australian science is contributing to America’s society and economy. You can download all of the factsheets as one PDF here.
  1. Overview: Innovation today means jobs and prosperity tomorrow. (Download PDF)
  2. Delivering sustainable agriculture and biosecurity. (Download PDF)
  3. Slivers of sun: clean energy and smarter mining. (Download PDF)
  4. Science collaboration improves health. (Download PDF)
  5. Understanding and responding to changing climate. (Download PDF)
  6. Traveling at Mach 5: Defense and materials science in action. (Download PDF)
  7. Searching the southern sky, and unchaining the internet. (Download PDF)
  8. The Australian science and technology system. (Download PDF)

Slivers of sun: clean energy and smarter mining

Klaus Weber (left) and Andrew Blakers (right) inventors of sliver solar cells. Credit: ANU
Klaus Weber (left) and Andrew Blakers (right) inventors of sliver solar cells. Credit: ANU

Australia’s investments in energy and resource research are helping the world go green, and creating jobs in America’s heartlands.

The world’s largest manufacturer of photovoltaic cells depends on Australian technology, and US companies are working on turning Australian ideas into practical electric cars and sustainable plant-based fuels.

Over the last 20 years Australia has been able to meet the rapidly growing demand for minerals and energy in China, India and other Asian countries through a culture of innovation that has over the past 150 years changed the very shape of mining.

Two recent innovations—one sourced from US military technology—are assisting in the search for new mineral and energy reserves in America and across the world.

Slivers of the Sun

Australia and the US have a long history as world leaders in solar research. In fact, researchers from the University of New South Wales (UNSW) in Sydney, the National Renewable Energy Laboratory in Colorado and Emcore Corporation in New Mexico have created the world’s most efficient solar cell combination. And the world’s largest photovoltaic cell manufacturer, Suntech Power of China, as well as companies in Europe, use Australian technology to develop their businesses.

Now, the new technologies are creating jobs in America. In June 2010, Transform Solar—a joint venture between US company Micron Technology and Australia’s Origin Energy—announced it will reopen a plant in Boise, Idaho to make efficient, new, sliver solar cells. As a consequence, the city looks like regaining many of the 3,000 jobs it lost when the factory closed.

Sliver cells were invented at the Australian National University (ANU) by Dr Klaus Weber and Professor Andrew Blakers. A single flat wafer of silicon is cut vertically into thousands of slivers. These are rotated 90 degrees and laid side by side to create a solar cell. The much larger and thinner active surface generates current on both sides, and the result is more power for about the same cost.

UltraBattery drives cars further

Ultrabattery at work. Credit: CSIRO
Ultrabattery at work. Credit: CSIRO

The UltraBattery, invented by CSIRO and launched in 2008, has brought the conventional car battery into the era of low-emission transport and renewable energy storage. By combining lead-acid technology with a supercapacitor, the UltraBattery not only charges and discharges rapidly, but lasts four to five times longer than an ordinary battery.

It also costs about 70 per cent less to produce than the nickel-metal hydride batteries normally used in electric vehicles. These properties, while especially useful for electric vehicles with regenerative braking, also are excellent for capturing and storing electricity produced from intermittent renewable sources, such as solar and wind power. In 2009, as part of a package to accelerate the production of advanced battery technology for electric and hybrid vehicles, the East Penn Manufacturing Company was awarded US$32.5 million under the American Recovery and Reinvestment Act to produce the UltraBattery.

Growing aircraft fuels

Aircraft manufacturer Boeing and California biotech company Amyris have joined the Queensland Government, the University of Queensland, the airline Virgin Blue, and several other companies in exploring the possibilities of producing aviation fuel sustainably using green algae. The project is based on the work of Associate Professor Ben Hankamer from the University of Queensland’s Institute of Molecular Bioscience and his team, who have had great success in improving the efficiency of the process.

At the Queensland University of Technology, Syngenta Biotechnology Inc of North Carolina and Australian company Farmacule are using molecular technologies to develop efficient ways of producing the transport fuel and chemical feedstock bioethanol from the sugarcane residue known as ‘bagasse’. The process is complicated and involves employing a string of enzymes to break down cellulose. But if the researchers get it right, the applications will extend to plant resources far beyond the waste generated by the sugar industry.

Finding tomorrow’s mines from the air

Tucson copper mine. Credit: istockphoto
Tucson copper mine. Credit: istockphoto

In the 1990s, Australian resources company BHP recognized that a sensor that measured minute changes in gravity, and hence density of the Earth below, might be useful as a means of discovering potential ore bodies in remote areas.

In 1999, BHP obtained a license to adapt to mineral exploration technology that originally had been developed by Lockheed Martin for the US Navy to help submarines avoid seamounts. The airborne sensor, which BHP named Falcon, has been responsible for discovering new diamond pipes in northwest Canada, and has assisted in detecting iron, copper, gold and coal deposits elsewhere.

Magnetic squid

Another Australian technology already out in the marketplace makes use of superconducting quantum interference device or SQUID technology that can detect extremely small magnetic fields. Known as LANDTEM and developed by CSIRO, the sensor, a high-temperature superconductor that must be stored in liquid nitrogen, is sensitive enough to detect the difference between an ore body and overburden. In less than 10 years the technology, which cost just AU$4 million to develop, has been directly responsible for helping to unearth about AU$6 billion worth of previously undiscovered ore bodies.

Mining with bubbles

In the 19th century, miners at Broken Hill in far western New South Wales pioneered the use of bubbles to separate minerals from their ores. This ubiquitous technology was modernized in the 1980s with the creation of the Jameson Cell by Dr Graeme Jameson at the University of Newcastle and Mount Isa Mines. The Vigo and A.T. Massey coal companies in Indiana and West Virginia respectively are among hundreds of mines worldwide now using this system marketed by Xstrata Technologies.

Making virtual minerals

Researchers at the University of Sydney led by Professor Dietmar Müller are collaborating with colleagues at Caltech, the Scripps Institution of Oceanography and the University of Hawaii to develop a Virtual Geological Observatory. The facility will store data on rocks, processes and movements over geological time and use this information to simulate mineral formation. In future, this technology will help in the detection of mineral deposits underground.

New extraction technologies

Once a new mineral deposit has been found, the next challenge is to determine which minerals you can extract and at what cost. The Australian Nuclear Science and Technology Organisation (ANSTO) has for the past 30 years been helping mining companies assess and develop processes for uranium ores, extract rare earth metals, and remove radioactivity from ores. This work has contributed to mining projects around the world, including the US.

Mopping up gases

Dr Deanna D’alessandro. Credit: L’oreal/SDP media
Dr Deanna D’alessandro. Credit: L’oreal/SDP media

A bright young researcher in the area of carbon capture is Australian chemist Dr Deanna D’Alessandro. Dr D’Alessandro, who has returned to the University of Sydney as a postdoctoral research fellow after a postdoctoral fellowship at the University of California, Berkeley, has constructed crystals full of minute pores. One teaspoon of the most effective of her chemicals has the surface area of a football field. What’s more, the size and shape of the pores can be customized using light. So, she believes she can create molecular sponges that will mop up carbon dioxide, hydrogen, or almost any gas, and then release it on cue.

This is an part of a series of eight factsheets exploring US-Australian collaboration and outlining some of the ways that Australian science is contributing to America’s society and economy. You can download all of the factsheets as one PDF here.

  1. Overview: Innovation today means jobs and prosperity tomorrow. (Download PDF)
  2. Delivering sustainable agriculture and biosecurity. (Download PDF)
  3. Slivers of sun: clean energy and smarter mining. (Download PDF)
  4. Science collaboration improves health. (Download PDF)
  5. Understanding and responding to changing climate. (Download PDF)
  6. Traveling at Mach 5: Defense and materials science in action. (Download PDF)
  7. Searching the southern sky, and unchaining the internet. (Download PDF)
  8. The Australian science and technology system. (Download PDF)

Strawberries that pack a flavour punch

Researchers are looking at the genetic and environmental factors that influence the taste of strawberries. Credit: RMIT
Researchers are looking at the genetic and environmental factors that influence the taste of strawberries. Credit: RMIT

Why does the same species of strawberry taste different in different countries? How is it that Californian strawberries are loved by locals but fail to impress Down Under?

RMIT University researchers, Assoc. Prof. Eddie Pang and Prof. Phil Marriott, are looking for answers to those questions to help Australian strawberry growers identify which breeds grow best in which region.

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Vaccine hope for shellfish allergies

Researchers are working with prawns in the search for a shellfish allergy vaccine. Credit: RMIT
Researchers are working with prawns in the search for a shellfish allergy vaccine. Credit: RMIT

A new oral vaccine against shellfish allergies is being developed by researchers at RMIT University.

Assoc. Prof. Andreas Lopata and his team in RMIT’s School of Applied Sciences are working to help find a different method for vaccination against the potentially deadly allergy.

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