Tag Archives: vaccine

Gastro discovery leads to worldwide vaccine rollout

Fifty million children in the world’s poorest countries will be vaccinated against the deadly rotavirus by 2015, thanks to the breakthrough work of a quiet Melbourne researcher.

Ruth Bishop. Credit: Stepping Stone Pictures

Ruth Bishop’s rotavirus discovery led to the development of the vaccine currently being rolled out by the Global Alliance for Vaccines and Immunisation—and to her declaration as 2013 CSL Florey Medal winner.

Each year, around half a million children die from rotavirus infection and the acute gastroenteritis it causes.

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A bug that stops dengue

Dengue fever is on the march and threatening the growing populations of Asia and even northern Australia. But a ‘vaccine’ for mosquitoes could stop it in its tracks.

Photo: A new ‘vaccine’ could stop mosquitos spreading dengue fever. Credit: Muhammad Mahdi Karim, Wikimedia, GNU Free Documentation Licence

A team of researchers from Melbourne, Brisbane, Cairns and Brazil has found a bacterium, Wolbachia, in fruit flies, which could stop mosquitoes from spreading dengue.

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A malaria vaccine target

Photo: Alan Cowman’s research may lead to a vaccine against the malaria parasite, which is transmitted by the Anopheles mosquito. Credit: Centers for Disease Control and Prevention, US Dept Health and Human Services

A vaccine is the holy grail of malaria control. Alan Cowman, of Melbourne’s Walter and Eliza Hall Institute, has discovered proteins that are key to the malaria parasite’s virulence, and therefore a potential vaccine target. He’s been able to weaken live parasites by manipulating their genes. It’s the culmination of over 20 years’ research into malaria and won Alan a $50,000 Victoria Prize.

Photo: Alan Cowman’s research may lead to a vaccine against the malaria parasite, which is transmitted by the Anopheles mosquito.
Credit: Centers for Disease Control and Prevention, US Dept Health and Human Services