Examining how individual heart cells develop is revealing how the cells make decisions to form a working heart.
Once an adult heart is damaged, it has no ability to heal itself. Dr Nathan Palpant at the Institute for Molecular Bioscience at the University of Queensland and Associate Professor Joseph Powell at the Garvan Institute of Medical Research and the University of New South Wales are trying to understand how that might be changed by tracking individual stem cells along their journey to becoming heart cells.
“Heart development is a difficult and complicated process, but we think the answers to heart repair are likely to lie in understanding heart development,” Nathan says. “So we are using stem cells to model development as it occurs in our bodies.” Continue reading Studying heart development one cell at a time→
Almost everyone has had their blood pressure measured with an inflatable cuff around the arm. But as useful as this is, it can differ from the reading at the heart itself.
Using a mathematical model to transform how we measure blood pressure. Credit: Mark Butlin
Twenty years ago Sydney scientists found a way to get that extra information. They created a model that gives the pressure at the main artery of the heart, using the wrist’s pressure pulse (the shape of the ‘waves’ that both travel along arteries when the heart pumps blood, and travel back to the heart as it fills with blood).
The model wasn’t applicable to children, since their limbs are still growing – so now they’re adapting it to fit.
