Tag Archives: genome

Why plumbers and teachers should have a say on designer babies and genetically enhanced potatoes

Ethical and social implications of powerful DNA-altering technology are too important to be left to scientists and politicians, researchers find.

Illustration by Alice Mollon

Designer babies, mutant mozzies and frankenfoods: these are the images that often spring to mind when people think of genome editing.

The practice – which alters an organism’s DNA in ways that could be inherited by subsequent generations – is both more complex and less dramatic than the popular tropes suggest.

However, its implications are so profound that a growing group of experts believe it is too important a matter to be left only to scientists, doctors and politicians.

Writing in the journal Science, 25 leading researchers from across the globe call for the creation of national and global “citizens’ assemblies”, made up of lay-people, tasked with considering the ethical and social impacts of this emerging science.

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The quest for the missing proteins in rice

Researchers have identified over 5,700 new proteins in rice and are calling for a global effort to find the remaining missing proteins, in a new study co-authored by Macquarie University.

The international team of scientists from Australia, Iran and Japan say there’s an estimated 35,000 proteins encoded by the rice genome, and yet we still don’t have experimental evidence for 82 per cent of them.

This is important because rice is the major food source for more than half the world’s population, and in order for it to grow in warmer climates and with less water we will need to better understand rice at the molecular level. Continue reading The quest for the missing proteins in rice

Widening the net on Motor Neurone Disease

Recent advances pinpointing genes involved in the inherited form of Motor Neurone Disease (MND) are now being used to hunt for the culprits of ‘sporadic’ cases.

Ian and his team are hunting the genes involved in Motor Neurone Disease. Credit: Paul Wright
Ian and his team are hunting the genes involved in Motor Neurone Disease.
Credit: Paul Wright

Sporadic MND is the most common form (around 90 per cent), and unlike the ‘familial,’ disease, it appears in patients without a family history.

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Genetics guiding anxiety treatment

For years we’ve been identifying genetic markers linked to mental disorders. Now it appears those same markers could also tell us who will best-respond to treatment.

Genetic data are another piece in the puzzle of personalised treatment for anxiety. Credit: Chris Stacey, Macquarie University
Genetic data are another piece in the puzzle of personalised treatment for anxiety. Credit: Chris Stacey, Macquarie University

A study of over 1,500 children, as part of the international Genes for Treatment collaboration, found those with a specific genetic marker were more responsive to psychological therapy than those without.

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Reading the Genome

Marnie Blewitt

The Walter & Eliza Hall Institute of Medical Research, Melbourne

Marnie Blewitt The Walter & Eliza Hall Institute of Medical Research, MelbourneMarnie Blewitt wants to know how a human being is made: how does a single fertilised egg develop into an adult with millions of cells performing a myriad of different functions. It’s the hottest issue in genetics, and one that’s close to her right now as she is expecting her first child soon.

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